Evidence map›Paper›PMID 23471609›Full record

ArticleBMJ open2013

Self-rated health and type 2 diabetes risk in the European Prospective Investigation into Cancer and Nutrition-InterAct study: a case-cohort study.

Patrik Wennberg, Olov Rolandsson, Daphne L van der A, Annemieke M W Spijkerman, Rudolf Kaaks, Heiner Boeing, Silke Feller, Manuela M Bergmann, Claudia Langenberg, Stephen J Sharp and 3 more

Abstract read
In one paragraph

Article in BMJ open, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  10. Genome-wide association studies in non-anxiety individuals identified novel risk loci for depression.European psychiatry : the journal of the Association of European Psychiatrists · 2022
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  18. Molecular genetic contributions to self-rated health.International journal of epidemiology · 2017
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  20. The joint association of self-rated health and diabetes status on 14-year mortality in elderly men and women.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2016
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Patrik WennbergDepartment of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden.
Olov Rolandsson
Daphne L van der A
Annemieke M W Spijkerman
Rudolf Kaaks
Heiner Boeing
Silke Feller
Manuela M Bergmann
Claudia Langenberg
Stephen J Sharp
Nita Forouhi
Elio Riboli
Nicholas Wareham

Funding

Medical Research Council MC_UP_A100_1003Medical Research Council MC_UU_12015/1Medical Research Council MC_UU_12015/5
6 · The paper itself

Abstract

objectivesTo investigate the association between self-rated health and risk of type 2 diabetes and whether the strength of this association is consistent across five European centres.

designPopulation-based prospective case-cohort study.

settingEnrolment took place between 1992 and 2000 in five European centres (Bilthoven, Cambridge, Heidelberg, Potsdam and Umeå).

participantsSelf-rated health was assessed by a baseline questionnaire in 3399 incident type 2 diabetic case participants and a centre-stratified subcohort of 4619 individuals from the European Prospective Investigation into Cancer and Nutrition (EPIC)-InterAct study which was drawn from a total cohort of 340 234 participants in the EPIC. PRIMARY OUTCOME MEASURE: Prentice-weighted Cox regression was used to estimate centre-specific HRs and 95% CIs for incident type 2 diabetes controlling for age, sex, centre, education, body mass index (BMI), smoking, alcohol consumption, energy intake, physical activity and hypertension. The centre-specific HRs were pooled across centres by random effects meta-analysis.

resultsLow self-rated health was associated with a higher hazard of type 2 diabetes after adjusting for age and sex (pooled HR 1.67, 95% CI 1.48 to 1.88). After additional adjustment for health-related variables including BMI, the association was attenuated but remained statistically significant (pooled HR 1.29, 95% CI 1.09 to 1.53). I(2) index for heterogeneity across centres was 13.3% (p=0.33).

conclusionsLow self-rated health was associated with a higher risk of type 2 diabetes. The association could be only partly explained by other health-related variables, of which obesity was the strongest. We found no indication of heterogeneity in the association between self-rated health and type 2 diabetes mellitus across the European centres.

Identifiers

PMID23471609
PMCPMC3612773

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.