ArticleFrontiers in physiology2013
Functional Development of the Octenol Response in Aedes aegypti.
Article in Frontiers in physiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
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Who cites it
32 citing papers in PubMed, 81 citations in OpenAlex.
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- A single-nucleus transcriptomic atlas of the adultbioRxiv : the preprint server for biology · 2025Article
- Context-dependent effects of carbon dioxide on cross-modal integration during mosquito flight.Scientific reports · 2025Article
- Knockout of OR39 reveals redundancy in the olfactory pathway regulating the acquisition of host seeking inProceedings. Biological sciences · 2023Article
- Mosquito host-seeking diel rhythm and chemosensory gene expression is affected by age and Plasmodium stages.Scientific reports · 2022Article
- Biting Innovations of Mosquito-Based Biomaterials and Medical Devices.Materials (Basel, Switzerland) · 2022Review
- Regulation of the antennal transcriptome of the dengue vector, Aedes aegypti, during the first gonotrophic cycle.BMC genomics · 2021Article
- Plasticity and modulation of olfactory circuits in insects.Cell and tissue research · 2021Review
- Modulation of odour-guided behaviour in mosquitoes.Cell and tissue research · 2021Review
- Highly sensitive VOC detectors using insect olfactory receptors reconstituted into lipid bilayers.Science advances · 2021Article
- The Role of Vector Trait Variation in Vector-Borne Disease Dynamics.Frontiers in ecology and evolution · 2020Article
- Transcriptomics supports local sensory regulation in the antenna of the kissing-bug Rhodnius prolixus.BMC genomics · 2020Article
- Age-dependent regulation of host seeking in Anopheles coluzzii.Scientific reports · 2019Article
- Cartography of odor chemicals in the dengue vector mosquito (Aedes aegypti L., Diptera/Culicidae).Scientific reports · 2019Article
- Attraction of FemaleInsects · 2019Article
- Sex and age modulate antennal chemosensory-related genes linked to the onset of host seeking in the yellow-fever mosquito, Aedes aegypti.Scientific reports · 2019Article
- Article
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Attraction of female Aedes aegypti mosquitoes to 1-octen-3-ol (octenol), CO2, lactic acid, or ammonia emitted by vertebrate hosts is not only contingent on the presence of odorants in the environment, but is also influenced by the insect's physiological state. For anautogenous mosquito species, like A. aegypti, newly emerged adult females neither respond to host odors nor engage in blood-feeding; the bases for these behaviors are poorly understood. Here we investigated detection of two components of an attractant blend emitted by vertebrate hosts, octenol, and CO2, by female A. aegypti mosquitoes using electrophysiological, behavioral, and molecular approaches. An increase in sensitivity of octenol olfactory receptor neurons (ORNs) was correlated with an increase in odorant receptor gene (Or) expression and octenol-mediated attractive behavior from day 1 to day 6 post-emergence. While the sensitivity of octenol ORNs was maintained through day 10, behavioral responses to octenol decreased as did the ability of females to discriminate between octenol and octenol + CO2. Our results show differing age-related roles for the peripheral receptors for octenol and higher order neural processing in the behavior of female mosquitoes.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.