ReviewEye (London, England)2013
A review of central retinal artery occlusion: clinical presentation and management.
Review in Eye (London, England), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 180 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
180 citing papers in PubMed, 5 syntheses or guidelines pooled it.
- The Neutrophil to Lymphocyte Ratio and Other Full Blood Count Indices in Retinal Diseases: A Systematic Review of the Literature.Medicina (Kaunas, Lithuania) · 2025Pooled it
- The Effects of Hyperbaric Oxygen Therapy in Patients with Central Retinal Artery Occlusion: A Retrospective Study, Systematic Review, and Meta-analysis.Korean journal of ophthalmology : KJO · 2022Pooled it
- Intravenous thrombolysis in patients with central retinal artery occlusion: a systematic review and meta-analysis.Journal of neurology · 2022Pooled it
- Treatment of retinal artery occlusion using transluminal Nd:YAG laser: a systematic review and meta-analysis.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2017Pooled it
- [Guidelines from the DOG, RG and BVA: retinal artery occlusion : November 2016 status].Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft · 2017Guideline
- Evaluation of Ophthalmic Artery Branch Retrograde Intervention in the Treatment of Central Retinal Artery Occlusion (CRAO).Medical science monitor : international medical journal of experimental and clinical research · 2017Trial
- Central retinal artery occlusion: meta-analysis of the risk of new-onset atrial fibrillation and ischemic stroke.Clinical research in cardiology : official journal of the German Cardiac Society · 2026Article
- Global research trends in central retinal artery occlusion: a bibliometric analysis (1980-2025).International ophthalmology · 2026Review
- Retinal, Vascular, and Choroidal Remodeling After Non-Reperfused Central Retinal Artery Occlusion: A Longitudinal OCT Study.Diagnostics (Basel, Switzerland) · 2026Article
- Real-Time High-Resolution OCT for Imaging Retinal and Choroidal Blood Flow.Investigative ophthalmology & visual science · 2026Article
- Comparative peripheral inflammatory biomarker profiles in central and branch retinal artery occlusion: a retrospective study.BMC ophthalmology · 2026Observational
- Ocular Color Doppler Ultrasound (OCDUS) in Diagnosis and Monitoring of Ophthalmological, Cerebrovascular and Systemic Diseases: A Narrative Review.Journal of clinical medicine · 2026Review
- Ocular massage in central retinal artery occlusion: Monitoring vascular recovery with optical coherence tomography angiography - A case series.American journal of ophthalmology case reports · 2026Article
- Risk of Retinal Vascular Occlusive Disease According to Type and Low-Density Lipoprotein-Cholesterol Control after Acute Coronary Syndrome.Yonsei medical journal · 2026Article
- Central Retinal Artery Occlusion Following Cosmetic Blepharoplasty in a Young Patient: A Case Report.Case reports in ophthalmological medicine · 2026Article
- Safety and Efficacy of Orally Administered SJP-0008 in Central Retinal Artery Occlusion: A Phase IIa Randomized Clinical Trial.Ophthalmology science · 2026Article
- Ophthalmic artery branches and adjacent nerves observed on sectioned images of cadaver.Anatomical science international · 2026Article
- How retinal artery occlusion reveals moyamoya disease-a case series and descriptive study.International journal of ophthalmology · 2026Article
- Observational
- Central Retinal Artery Occlusion in the Emergency Department: A Case Report of Prompt Diagnosis and Treatment.Cureus · 2025Article
120 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Central retinal artery occlusion (CRAO) is an ophthalmic emergency and the ocular analogue of cerebral stroke. Best evidence reflects that over three-quarters of patients suffer profound acute visual loss with a visual acuity of 20/400 or worse. This results in a reduced functional capacity and quality of life. There is also an increased risk of subsequent cerebral stroke and ischaemic heart disease. There are no current guideline-endorsed therapies, although the use of tissue plasminogen activator (tPA) has been investigated in two randomized controlled trials. This review will describe the pathophysiology, epidemiology, and clinical features of CRAO, and discuss current and future treatments, including the use of tPA in further clinical trials.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.