Trial reportBiological psychology2013
Posttraumatic stress disorder and partner-specific social cognition: a pilot study of sex differences in the impact of arginine vasopressin.
Trial report in Biological psychology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 24 citations in OpenAlex.
- Effects of arginine vasopressin on human anxiety and associations with sex, dose, and V1a-receptor genotype.Psychopharmacology · 2024Trial
- Biomarkers for complex post-traumatic stress disorder: translational and evolutionary perspectives.Frontiers in psychiatry · 2026Article
- Limbic Neuropeptidergic Modulators of Emotion and Their Therapeutic Potential for Anxiety and Post-Traumatic Stress Disorder.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021Review
- Sex-Specific Vasopressin Signaling Buffers Stress-Dependent Synaptic Changes in Female Mice.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2020Article
- Posttraumatic stress disorder and relationship functioning: A comprehensive review and organizational framework.Clinical psychology review · 2018Review
- Imaging, Behavior and Endocrine Analysis of "Jealousy" in a Monogamous Primate.Frontiers in ecology and evolution · 2017Article
- Serotonin and arginine-vasopressin mediate sex differences in the regulation of dominance and aggression by the social brain.Proceedings of the National Academy of Sciences of the United States of America · 2016Article
- Vasopressin and oxytocin receptor systems in the brain: Sex differences and sex-specific regulation of social behavior.Frontiers in neuroendocrinology · 2016Review
- Oxytocin and MDMA ('Ecstasy') enhance social reward in rats.Psychopharmacology · 2015Article
- Species, sex and individual differences in the vasotocin/vasopressin system: relationship to neurochemical signaling in the social behavior neural network.Frontiers in neuroendocrinology · 2015Review
- Hypothalamic vasopressin systems are more sensitive to the long term effects of social defeat in males versus females.Psychoneuroendocrinology · 2015Article
- Epigenetic Risk Factors in PTSD and Depression.Frontiers in psychiatry · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
Posttraumatic stress disorder (PTSD) is associated with problems in intimate relationships, partly due to deficits in social cognition. In this study, the role of arginine vasopressin (AVP) in the link between PTSD and partner-specific social cognition was examined. Participants were 24 individuals from 12 heterosexual couples in which at least one partner exhibited clinically significant PTSD symptoms. Attention to partner expressions of anger was examined as an indicator of distress and need for affiliative behaviors to repair the relationship bond. AVP administration improved the speed of men's attentional engagement with their partners' expressions of anger and alleviated the negative impact of PTSD on this social cognitive process. Further, men's morning urinary AVP levels were negatively correlated with their PTSD severity. No such effects were found among women or for attention to unfamiliar men's or women's anger expressions. Thus, the AVP system may function in the relationship problems associated with PTSD.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.