ReviewMedicine and science in sports and exercise2013
Advances in exercise, fitness, and performance genomics in 2012.
Review in Medicine and science in sports and exercise, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 57 citations in OpenAlex.
- Genetics and athletic performance: a systematic SWOT analysis of non-systematic reviews.Frontiers in genetics · 2023Pooled it
- Genetic profiles to identify talents in elite endurance athletes and professional football players.PloS one · 2022Article
- Article
- Prediction and Identification of Power Performance Using Polygenic Models of Three Single-Nucleotide Polymorphisms in Chinese Elite Athletes.Frontiers in genetics · 2021Article
- Association of whole mtDNA, an NADPH G11914A variant, and haplogroups with high physical performance in an elite military troop.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2021Article
- Article
- Reply to the Letter to the Editor on "Effects of Light-Emitting Diode Therapy on Muscle Hypertrophy, Gene Expression, Performance, Damage, and Delayed-Onset Muscle Soreness: Case-Control Study With a Pair of Identical Twins".American journal of physical medicine & rehabilitation · 2018Article
- A Medal in the Olympics Runs in the Family: A Cohort Study of Performance Heritability in the Games History.Frontiers in physiology · 2018Article
- Exploring the relationship between α-actinin-3 deficiency and obesity in mice and humans.International journal of obesity (2005) · 2017Article
- Endurance Exercise Ability in the Horse: A Trait with Complex Polygenic Determinism.Frontiers in genetics · 2017Article
- Effects of Light-Emitting Diode Therapy on Muscle Hypertrophy, Gene Expression, Performance, Damage, and Delayed-Onset Muscle Soreness: Case-control Study with a Pair of Identical Twins.American journal of physical medicine & rehabilitation · 2016Article
- Genetic variants influencing effectiveness of exercise training programmes in obesity - an overview of human studies.Biology of sport · 2016Review
- Direct-to-consumer genetic testing for predicting sports performance and talent identification: Consensus statement.British journal of sports medicine · 2015Article
- Advances in exercise, fitness, and performance genomics in 2014.Medicine and science in sports and exercise · 2015Review
- Genetic variations underlying self-reported physical functioning: a review.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2015Review
- Article
- Likely additive ergogenic effects of combined preexercise dietary nitrate and caffeine ingestion in trained cyclists.ISRN nutrition · 2013Article
- Personalized lifestyle medicine: relevance for nutrition and lifestyle recommendations.TheScientificWorldJournal · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 4 institutions in 2 countries.
Funding
Abstract
A small number of excellent articles on exercise genomics issues were published in 2012. A new PYGM knock-in mouse model will provide opportunities to investigate the exercise intolerance and very low activity level of people with McArdle disease. New reports on variants in ACTN3 and ACE have increased the level of uncertainty regarding their true role in skeletal muscle metabolism and strength traits. The evidence continues to accumulate on the positive effects of regular physical activity on body mass index or adiposity in individuals at risk of obesity as assessed by their FTO genotype or by the number of risk alleles they carry at multiple obesity-susceptibility loci. The serum levels of triglycerides and the risk of hypertriglyceridemia were shown to be influenced by the interactions between a single nucleotide polymorphism (SNP) in the NOS3 gene and physical activity level. Allelic variation at nine SNPs was shown to account for the heritable component of the changes in submaximal exercise heart rate induced by the HERITAGE Family Study exercise program. SNPs at the RBPMS, YWHAQ, and CREB1 loci were found to be particularly strong predictors of the changes in submaximal exercise heart rate. The 2012 review ends with comments on the importance of relying more on experimental data, the urgency of identifying panels of genomic predictors of the response to regular exercise and particularly of adverse responses, and the exciting opportunities offered by recent advances in our understanding of the global architecture of the human genome as reported by the Encyclopedia of DNA Elements project.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.