Trial reportPublic health nutrition2013
Plasma zinc, vitamin B(12) and α-tocopherol are positively and plasma γ-tocopherol is negatively associated with Hb concentration in early pregnancy in north-west Bangladesh.
Trial report in Public health nutrition, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed, 41 citations in OpenAlex.
- Antenatal Multiple Micronutrient Supplementation Compared to Iron-Folic Acid Affects Micronutrient Status but Does Not Eliminate Deficiencies in a Randomized Controlled Trial Among Pregnant Women of Rural Bangladesh.The Journal of nutrition · 2019Trial
- Diet Quality as an Associated Factor for Liver Function Enzyme Abnormalities Among Women of Reproductive Age.Cureus · 2026Article
- Dietary Energy and Nutrient Intake Among Pregnant Women in Sri Lanka: Findings From the Sri Lanka Mother and Newborn Growth Cohort Study.Journal of human nutrition and dietetics : the official journal of the British Dietetic Association · 2025Article
- Association between micronutrient supplementation during pregnancy and preterm birth: evidence from a large-scale children survey and Mendelian randomization study.Frontiers in public health · 2025Article
- Perinatal inflammation, fetal growth restriction, and long-term neurodevelopmental impairment in Bangladesh.Pediatric research · 2024Article
- Dietary vitamin A intake and its major food sources among rural pregnant women of South-West Bangladesh.Heliyon · 2023Article
- Associations of serum concentrations of metal nutrients with postpartum anemia among pregnant Chinese women: A large retrospective cohort study.Frontiers in nutrition · 2023Article
- Prevalence and Risk Factors of Vitamin BNutrients · 2022Article
- Article
- Maternal Diet, Infection, and Risk of Cord Blood Inflammation in the Bangladesh Projahnmo Pregnancy Cohort.Nutrients · 2021Article
- Vitamin BNutrients · 2020Article
- Article
- Plasma versus Erythrocyte Vitamin E in Renal Transplant Recipients, and Duality of Tocopherol Species.Nutrients · 2019Article
- Maternal BMI and nutritional status in early pregnancy and its impact on neonatal outcomes at birth in Bangladesh.BMC pregnancy and childbirth · 2019Article
- Micronutrient deficiencies in pregnancy worldwide: health effects and prevention.Nature reviews. Endocrinology · 2016Review
- Maternal Micronutrient Supplementation and Long Term Health Impact in Children in Rural Bangladesh.PloS one · 2016Article
- Vitamin E inadequacy in humans: causes and consequences.Advances in nutrition (Bethesda, Md.) · 2014Review
- Diet and nutritional status during pregnancy.Public health nutrition · 2013Article
- Genetic susceptible locus in NOTCH2 interacts with arsenic in drinking water on risk of type 2 diabetes.PloS one · 2013Article
- Vitamin E deficiency in South Asian population and the therapeutic use of alpha-tocopherol (Vitamin E) for correction of anemia.Pakistan journal of medical sciencesReview
Corrections and comments
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Authors and funding
9 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe objective of the current analysis was to explore the association of multiple micronutrients with Hb concentration among pregnant women in a South Asian setting, a topic that has not been adequately explored.
designSociodemographic, anthropometric and micronutrient status (plasma ferritin, transferrin receptor, retinol, a- and g-tocopherol, folate, vitamin B12, Zn) and Hb concentration were assessed at early pregnancy.
settingThe biochemical sub-study was nested within a double-blind, placebo-controlled, community-based vitamin A and b-carotene supplementation trial in rural north-western Bangladesh (JiVitA). All assessments were conducted before trial supplementation was initiated. SUBJECTS: A systematic sample of 285 women was selected from those enrolled in the biochemical sub-study.
resultsSeventeen per cent of women were mildly anaemic; moderate and severe anaemia was uncommon (2.1 %). a-Tocopherol, vitamin B12 and Zn deficiencies were common (43.5%, 19.7% and 14.7%, respectively); however, vitamin A, folate and Fe deficiencies were comparatively rare (7.4%, 2.8% and ,1%,respectively). Plasma Zn, vitamin B12 and a-tocopherol were positively associated and plasma g-tocopherol was negatively associated with Hb (P < 0.05) after adjustment for gestational age, inflammation status, season and nutritional status measured by mid-upper arm circumference.
conclusionsAmong pregnant women in rural Bangladesh with minimal Fe deficiency, plasma Zn, vitamin B12, and a- and g-tocopherol concentrations were associated with Hb concentration. Appreciating the influence on Hb of micronutrients in addition to those with known associations with anaemia, such as Fe, folate, and vitamin A, is important when addressing anaemia in similar settings.
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