ArticleJournal of cognitive neuroscience2013
The impact of neurodegeneration on network connectivity: a study of change detection in frontotemporal dementia.
Article in Journal of cognitive neuroscience, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
32 citing papers in PubMed, 72 citations in OpenAlex.
- GABA-ergic Dynamics in Human Frontotemporal Networks Confirmed by Pharmaco-Magnetoencephalography.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2020Trial
- Towards affordable biomarkers of frontotemporal dementia: A classification study via network's information sharing.Scientific reports · 2017Trial
- Improving response inhibition systems in frontotemporal dementia with citalopram.Brain : a journal of neurology · 2015Trial
- Alzheimer's disease and memantine effects on NMDA-receptor blockade: non-invasive in vivo insights from magnetoencephalography.Molecular psychiatry · 2026Article
- Subjective time perception in dementia: a behavioural and neuroanatomical analysis.Brain communications · 2026Article
- Alzheimer's disease and its progression reduce pyramidal cell gain and connectivity.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Article
- The pursuit for markers of disease progression in behavioral variant frontotemporal dementia: a scoping review to optimize outcome measures for clinical trials.Frontiers in aging neuroscience · 2024Article
- Frontotemporal lobar degeneration changes neuronal beta-frequency dynamics during the mismatch negativity response.NeuroImage. Clinical · 2024Article
- Distinct neurophysiology during nonword repetition in logopenic and non-fluent variants of primary progressive aphasia.Human brain mapping · 2023Article
- Neurophysiological consequences of synapse loss in progressive supranuclear palsy.Brain : a journal of neurology · 2023Article
- New Therapeutics in Alzheimer's Disease Longitudinal Cohort study (NTAD): study protocol.BMJ open · 2022Article
- Exploring electrophysiological markers of auditory predictive processes and pathological ageing in adults with Down's syndrome.The European journal of neuroscience · 2022Article
- A multi-site, multi-participant magnetoencephalography resting-state dataset to study dementia: The BioFIND dataset.NeuroImage · 2022Article
- The neurophysiological effect of NMDA-R antagonism of frontotemporal lobar degeneration is conditional on individual GABA concentration.Translational psychiatry · 2022Article
- Neurophysiological and Brain Structural Markers of Cognitive Frailty Differ from Alzheimer's Disease.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2022Article
- Entropy, Amnesia, and Abnormal Déjà Experiences.Frontiers in psychology · 2022Article
- Evidence and implications of abnormal predictive coding in dementia.Brain : a journal of neurology · 2021Review
- In Vivo Assay of Cortical Microcircuitry in Frontotemporal Dementia: A Platform for Experimental Medicine Studies.Cerebral cortex (New York, N.Y. : 1991) · 2021Article
- Decoding expectation and surprise in dementia: the paradigm of music.Brain communications · 2021Article
- Gamma-induction in frontotemporal dementia (GIFTeD) randomized placebo-controlled trial: Rationale, noninvasive brain stimulation protocol, and study design.Alzheimer's & dementia (New York, N. Y.) · 2021Article
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
Abstract
The neural response to unpredictable auditory events is suggested to depend on frontotemporal interactions. We used magnetoencephalography in patients with behavioral variant frontotemporal dementia to study change detection and to examine the impact of disease on macroscopic network connectivity underlying this core cognitive function. In patients, the amplitudes of auditory cortical responses to predictable standard tones were normal but were reduced for unpredictable deviant tones. Network connectivity, in terms of coherence among frontal, temporal, and parietal sources, was also abnormal in patients. In the beta frequency range, left frontotemporal coherence was reduced. In the gamma frequency range, frontal interhemispheric coherence was reduced whereas parietal interhemispheric coherence was enhanced. These results suggest impaired change detection resulting from dysfunctional frontotemporal interactions. They also provide evidence of a rostro-caudal reorganization of brain networks in disease. The sensitivity of magnetoencephalography to cortical network changes in behavioral variant frontotemporal dementia enriches the understanding of neurocognitive systems as well as showing potential for studies of experimental therapies for neurodegenerative disease.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.