ArticlePloS one2013
Effects of gender on severity, management and outcome in acute biliary pancreatitis.
Article in PloS one, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.
- Alcohol Consumption as a Risk Factor for Acute and Chronic Pancreatitis: A Systematic Review and a Series of Meta-analyses.EBioMedicine · 2015Pooled it
- Article
- Trends in the global, regional, and national burden of pancreatitis among children and adolescents based on the GBD 2021.International journal of surgery (London, England) · 2026Article
- Phospholipase D2: A biomarker implicated in various pancreatic diseases beyond acute pancreatitis.World journal of gastroenterology · 2025Article
- Association between neutrophil to high-density lipoprotein cholesterol ratio and disease severity in patients with acute biliary pancreatitis.Annals of medicine · 2024Article
- Neutrophil-Creatinine Index: A New Prognostic Factor for Severity of Acute Pancreatitis.Medicina (Kaunas, Lithuania) · 2024Article
- Readmissions After Biliary Acute Pancreatitis: Analysis of the Nationwide Readmissions Database.Gastroenterology research · 2022Article
- Loss of LAT1 sex-dependently delays recovery after caerulein-induced acute pancreatitis.World journal of gastroenterology · 2022Article
- Secondary ARDS Following Acute Pancreatitis: Is Extracorporeal Membrane Oxygenation Feasible or Futile?Journal of clinical medicine · 2021Article
- Sex-Related Differences of Acute and Chronic Pancreatitis in Adults.Journal of clinical medicine · 2021Review
- Ringer's Lactate Prevents Early Organ Failure by Providing Extracellular Calcium.Journal of clinical medicine · 2020Article
- Acute pancreatitis. A more common and severe complication of gallstones in males.International journal of health sciences · 2015Article
- Integrated traditional Chinese medicine improves acute pancreatitis via the downregulation of PRSS1 and SPINK1.Experimental and therapeutic medicine · 2015Article
- Biliary pancreatitis. Deadly threat to the elderly. Is it a real threat?International journal of health sciences · 2015Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundWe conducted a population-based cross-sectional study to examine gender differences in severity, management, and outcome among patients with acute biliary pancreatitis (ABP) because available data are insufficient and conflicting.
methodsWe analyzed 13,110 patients (50.6% male) with first-attack ABP from Taiwan's National Health Insurance Research Database between 2000 and 2009. The primary outcome was hospital mortality. Secondary outcomes included the development of severe ABP and the provision of treatment measures. Gender difference was assessed using multivariable analyses with generalized estimating equations models.
resultsThe odds of gastrointestinal bleeding (adjusted odds ratio [aOR] 1.44, 95% confidence interval [CI] 1.18-1.76) and local complication (aOR 1.38, 95% CI 1.05-1.82) were 44% and 38% higher in men than in women, respectively. Compared with women, men had 24% higher odds of receiving total parenteral nutrition (aOR 1.24, 95% CI 1.00-1.52), but had 18% and 41% lower odds of receiving cholecystectomy (aOR 0.82, 95% CI 0.72-0.93) and hemodialysis (aOR 0.59, 95% CI 0.42-0.83), respectively. Hospital mortality was higher in men than in women (1.8% vs. 1.1%, p = 0.001). After adjustment for potential confounders, men had 81% higher odds of in-hospital death than women (aOR 1.81, 95% CI 1.15-2.86). Among patients with severe ABP, hospital mortality was 11.0% and 7.5% in men and women (p<0.001), respectively. The adjusted odds of death remained higher in men than in women with severe ABP (aOR 1.72, 95% CI 1.10-2.68).
conclusionsGender is an important determinant of outcome in patients with ABP and may affect their treatment measures.
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