ArticlePloS one2013
The Pacific Ocean virome (POV): a marine viral metagenomic dataset and associated protein clusters for quantitative viral ecology.
Article in PloS one, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 187 papers.
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Who cites it
187 citing papers in PubMed.
- Elevation-structured viral ecological strategies along glacier-fed rivers on the Qinghai-Tibet Plateau.Nature communications · 2026Article
- Diversity of RNA Viruses in Declining Mediterranean Forests.Microorganisms · 2026Article
- Viral Dark Matter: Illuminating Protein Function, Ecology, and Biotechnological Promises.Biochemistry · 2025Review
- Biogeography of Virioplankton Abundance and Subcluster Patterns in the Northwest Pacific: A Large-Scale Perspective.MicrobiologyOpen · 2025Article
- Depth-driven decline in viral diversity unveils potential novel viruses in global deep-sea ecosystems.Microbiology (Reading, England) · 2025Article
- Viral ecogenomics across oxic and anoxic zones of the Yongle Blue Hole.Environmental microbiome · 2025Article
- Viral Dark Matter: Illuminating Protein Function, Ecology, and Biotechnological Promises.ArXiv · 2025Article
- Diversity and distribution of a prevalent Microviridae group across the global oceans.Communications biology · 2024Article
- MVP: a modular viromics pipeline to identify, filter, cluster, annotate, and bin viruses from metagenomes.mSystems · 2024Article
- Viromes vs. mixed community metagenomes: choice of method dictates interpretation of viral community ecology.Microbiome · 2024Article
- Entourage: all-in-one sequence analysis software for genome assembly, virus detection, virus discovery, and intrasample variation profiling.BMC bioinformatics · 2024Article
- Giant viral signatures on the Greenland ice sheet.Microbiome · 2024Article
- Long-read powered viral metagenomics in the oligotrophic Sargasso Sea.Nature communications · 2024Article
- Prophage enhances the ability of deep-sea bacteriumMicrobiology spectrum · 2024Article
- A rumen virosphere with implications of contribution to fermentation and methane production, and endemism in cattle breeds and individuals.Applied and environmental microbiology · 2024Article
- The Diversity of Bacteriophages in Hot Springs.Methods in molecular biology (Clifton, N.J.) · 2024Review
- Tools and methodology toFrontiers in microbiology · 2024Review
- Viromes vs. mixed community metagenomes: choice of method dictates interpretation of viral community ecology.bioRxiv : the preprint server for biology · 2023Article
- Genomic diversity and biogeographic distributions of a novel lineage of bacteriophages that infect marine OM43 bacteria.Microbiology spectrum · 2023Article
- A systematic analysis of marine lysogens and proviruses.Nature communications · 2023Article
127 more citing papers are in PubMed but not listed here.
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Bacteria and their viruses (phage) are fundamental drivers of many ecosystem processes including global biogeochemistry and horizontal gene transfer. While databases and resources for studying function in uncultured bacterial communities are relatively advanced, many fewer exist for their viral counterparts. The issue is largely technical in that the majority (often 90%) of viral sequences are functionally 'unknown' making viruses a virtually untapped resource of functional and physiological information. Here, we provide a community resource that organizes this unknown sequence space into 27 K high confidence protein clusters using 32 viral metagenomes from four biogeographic regions in the Pacific Ocean that vary by season, depth, and proximity to land, and include some of the first deep pelagic ocean viral metagenomes. These protein clusters more than double currently available viral protein clusters, including those from environmental datasets. Further, a protein cluster guided analysis of functional diversity revealed that richness decreased (i) from deep to surface waters, (ii) from winter to summer, (iii) and with distance from shore in surface waters only. These data provide a framework from which to draw on for future metadata-enabled functional inquiries of the vast viral unknown.
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