ArticleJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology2013
Coronary artery and thoracic aorta calcification is inversely related to coronary flow reserve as measured by ⁸²Rb PET/CT in intermediate risk patients.
Article in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
10 citing papers in PubMed, 13 citations in OpenAlex.
- Circulating osteoprotegerin and progression of coronary artery calcification in patients with chronic kidney disease: the KoreaN Cohort Study for Outcome in Patients With Chronic Kidney Disease (KNOW-CKD).Kidney research and clinical practice · 2026Article
- Navigating the Crossroads: Understanding the Link Between Chronic Kidney Disease and Cardiovascular Health.Cureus · 2023Review
- Coronary artery calcium score and pre-test probabilities as gatekeepers to predict and rule out perfusion defects in positron emission tomography.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023Article
- The power of zero calcium in 82-Rubidium PET irrespective of sex and age.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023Article
- Vascular pathologies in chronic kidney disease: pathophysiological mechanisms and novel therapeutic approaches.Journal of molecular medicine (Berlin, Germany) · 2021Review
- Article
- Characteristics of coronary artery disease in chronic kidney disease.Clinical and experimental nephrology · 2019Review
- Impaired myocardial perfusion is associated with increasing end-systolic- and end-diastolic volumes in patients with non-ischemic systolic heart failure: a cross-sectional study using Rubidium-82 PET/CT.BMC cardiovascular disorders · 2019Article
- Article
- Advanced tracers in PET imaging of cardiovascular disease.BioMed research international · 2014Review
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Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe strength and nature of the relationship between myocardial perfusion imaging (MPI), coronary flow reserve (CFR), and coronary artery calcium (CAC) and thoracic aorta calcium (TAC) remain to be clarified.
methodsDynamic rest-pharmacological stress (82)Rb positron emission tomography/computed tomography MPI with CFR, CAC, and TAC was performed in 75 patients (59 ± 13 years; F/M = 38/37) with intermediate risk of coronary artery disease.
resultsA total of 29 (39%) patients had ischemic and 46 (61%) had normal MPI. CAC was correlated with TAC (ρ = 0.7; P < .001), and CFR was inversely related with CAC and TAC (ρ = -0.6 and -0.5; P < .001, respectively). By gender-specific univariate analysis, age (P = .001), CAC (P = .004), and CFR (P = .008) in males, but CFR (P = .0001), age (P = .002), and TAC (P = .01) in females were significant predictors of ischemic MPI. By multiple regression, the most potent predictor was CFR [odds ratio (OR) = 0.17, P = .01), followed by age (OR = 1.07, P = .02), gender (OR = 4.01, P = .03), and CAC (OR = 1.002, P = .9).
conclusionsCombination of MPI, CFR, CAC, and TAC has complementary roles in intermediate risk patients.
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