ArticleEuropean journal of immunology2013
Development of CD27+ marginal zone B cells requires GALT.
Article in European journal of immunology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
7 citing papers in PubMed, 11 citations in OpenAlex.
- Article
- Spatiotemporal segregation of human marginal zone and memory B cell populations in lymphoid tissue.Nature communications · 2018Article
- Apoptotic cell responses in the splenic marginal zone: a paradigm for immunologic reactions to apoptotic antigens with implications for autoimmunity.Immunological reviews · 2016Review
- Human spleen microanatomy: why mice do not suffice.Immunology · 2015Review
- Phenotypes and distribution of mucosal memory B-cell populations in the SIV/SHIV rhesus macaque model.Clinical immunology (Orlando, Fla.) · 2014Article
- Innate lymphoid cells integrate stromal and immunological signals to enhance antibody production by splenic marginal zone B cells.Nature immunology · 2014Article
- The B cell helper side of neutrophils.Journal of leukocyte biology · 2013Review
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
In species other than mouse, little is known about the origin and development of marginal zone (MZ) B cells. Using cross-reactive antibodies, we identified and characterized splenic MZ B cells in rabbits as CD27(+) CD23(-). In rabbits in which organized gut-associated lymphoid tissue (GALT) was surgically removed at birth, we found only CD23(+) follicular (FO) B cells and almost no CD27(+) MZ B cells in the spleen, indicating that GALT is required for the development of splenic MZ B cells. These findings lead us to suggest that commensal microbiota contribute to the development of MZ B cells.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.