Trial reportUrolithiasis2013
Stone expulsion rate of small distal ureteric calculi could be predicted with plasma C-reactive protein.
Trial report in Urolithiasis, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 2 syntheses or guidelines pooled it, 45 citations in OpenAlex.
- Neutrophil to lymphocyte ratio in urolithiasis: a systematic review.BMC urology · 2025Pooled it
- Predictive value of inflammatory markers for the spontaneous passage of Ureteral stones: a comprehensive systematic review with meta analysis.Urolithiasis · 2024Pooled it
- Role of ureteral wall thickness and computed tomography imaging in predicting spontaneous passage of ureteral stones.Diagnostic and interventional radiology (Ankara, Turkey) · 2026Article
- Article
- Article
- Current Status of Protein Biomarkers in Urolithiasis-A Review of the Recent Literature.Journal of clinical medicine · 2023Review
- A machine learning model for predicting surgical intervention in renal colic due to ureteral stone(s) < 5 mm.Scientific reports · 2022Article
- When should we give up on expectant management for patients with proximal ureteral stones?Current urology · 2022Article
- Article
- Clinical and Radiological Predictors of Early Intervention in Acute Ureteral Colic.International journal of general medicine · 2021Article
- A neural network-based algorithm for predicting the spontaneous passage of ureteral stones.Urolithiasis · 2020Article
- Can serum procalcitonin levels be useful in predicting spontaneous ureteral stone passage?BMC urology · 2020Observational
- Association of spontaneous expulsion with C-reactive protein and other clinico-demographic factors in patients with lower ureteric stone.Urolithiasis · 2020Observational
- Inflammatory serum markers predicting spontaneous ureteral stone passage.Clinical and experimental nephrology · 2020Article
- Predictors of surgical intervention following initial surveillance for acute ureteric colic.World journal of urology · 2018Article
- Size matters: The width and location of a ureteral stone accurately predict the chance of spontaneous passage.European radiology · 2017Article
- Significance of Neutrophil-to-Lymphocyte Ratio as a Novel Indicator of Spontaneous Ureter Stone Passage.Yonsei medical journal · 2017Article
- A multi-centre cohort study evaluating the role of inflammatory markers in patient's presenting with acute ureteric colic (MIMIC).International journal of surgery protocols · 2017Article
- Medical expulsive therapy.Indian journal of urology : IJU : journal of the Urological Society of India · 2014Article
- Letter to the Editor: Relationship Between Spontaneous Passage Rates of Ureteral Stones Less Than 8 mm and Serum C-Reactive Protein Levels and Neutrophil Percentages.Korean journal of urology · 2013Article
Corrections and comments
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Authors and funding
1 author at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Ureteral stones tend to induce inflammatory lesions in the ureteric wall; such lesions may interfere with the probability of spontaneous ureteral stone passage. Plasma C-reactive protein (CRP) is an acute-phase protein whose serum level is increases in response to inflammation, as in ureteric inflammatory disorders induced by stone impaction. Patients with distal ureteric stones were included in this study. All patients were subjected to history taking KUB, urinary tract ultrasound, Non-contrast CT (NC-CTKUB) scan, and plasma CRP estimation. All patients received medical expulsive therapy. Patients were examined weekly using KUB and urinary tract ultrasound until spontaneous stone passage or intervention after 4 weeks. Patients who failed to expel the stone within 4 weeks underwent ureteroscopy. Spontaneous stone expulsion within 4 weeks was recorded in 129 patients (54.9 %), while 106 patients (45.1 %) underwent ureteroscopy for stone extraction. Patients with spontaneous stone expulsion had significantly lower serum CRP levels (16.45 + 2.58) than those who failed to pass the stone spontaneously (39.67 + 6.30). Receiver operator characteristic curve is used to determine CRP cut-off point for prediction of spontaneous ureteric stone expulsion. A cut-off point of 21.9 mg/L for CRP yielded appeared optimal for prediction of spontaneous ureteric stone expulsion. Medical expulsive therapy success for management of small distal ureteric calculi could be predicted with plasma CRP. Patients with CRP >21.9 mg/L have low stone expulsion rate and should directly be subjected for an immediate, minimally invasive ureteroscopy.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.