Evidence map›Paper›PMID 23468141›Full record

ReviewDepression and anxiety2013

The breathing conundrum-interoceptive sensitivity and anxiety.

Martin P Paulus

Registry-linked trialAbstract readReview
In one paragraph

Review in Depression and anxiety, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02786771 (Exploring the Effects of Muse and Spire on Stress Management), which is not on this map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02786771 nacompletednot on this mapstarted 2016, after this paper: background citation

Exploring the Effects of Muse and Spire on Stress Management

TypeinterventionalSponsorMassachusetts General HospitalRan2016 to 2016Enrolled126ConditionsStressArmsSpire, Muse headband
3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 93 citations in OpenAlex.

  1. Trial
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Microstructural Brain Correlates of Inter-individual Differences in Respiratory Interoception.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
    Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Martin P PaulusUniversity of California, San Diego, California; Veterans Affairs San Diego Health Care System, San Diego, CA 92093, USA. mpaulus@ucsd.edu
University of California, San Diego · US

Funding

Neuroimaging CoreP20DA027843 · NIDA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI PAULUS, MARTIN P. · 2010 to 2013
$3.5M
Negative reinforcement and interoceptive dysfunction in stimulant dependence.R01DA027797 · NIDA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI PAULUS, MARTIN P. · 2009 to 2013
$1.7M
NIDA NIH HHS P20 DA027843NIDA NIH HHS R01 DA027797
6 · The paper itself

Abstract

Cognitive and affective processing has been the central focus of brain-related functions in psychology and psychiatry for many years. Much less attention has been paid to what could be considered the primary function of the brain, to regulate the function of the body. Recent developments, which include the conceptualization of interoception as a process consisting of integrating the information coming from the inside of the body in the central nervous system and the appreciation that complex emotional processes are fundamentally affected by the processing and regulation of somatic states, have profoundly changed the view of the function and dysfunction of the brain. This review focuses on the relationship between breathing and anxiety. Several anxiety disorders have been associated with altered breathing, perception of breathing, and response to manipulations of breathing. Both clinical and experimental research studies are reviewed that relate breathing dysfunctions to anxiety. Altered breathing may be useful as a physiological marker of anxiety as well as a treatment target using interoceptive interventions.

Indexed as

RespirationAnxietyBrainHumansProprioceptionSensationSomatosensory Disorders

Identifiers

PMID23468141
PMCPMC3805119
OpenAlexW2095696374

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.