ArticleHNO2013
[Tissue engineering using porous polyethylene implants].
Article in HNO, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed, 4 citations in OpenAlex.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Although porous polyethylene (PPE) implants are already used in reconstructive craniofacial surgery, they are still only applied in rhinoplasty when critically indicated. Biocompatibility of PPE implants (pore size ~100-200 µm) can be modified by tissue engineering: coatings with extracellular matrix components, growth factors, anti-inflammatory substances and living cells are all possible. At present, transparent dorsal skinfold chamber models in animals appear to be particularly appropriate for pre-clinical evaluation. Using in vivo fluorescence microscopy, angiogenic microvascular ingrowth and inflammatory leukocyte-endothelial cell interactions can be analysed in detail with regard to functionally relevant mechanical integration. Preclinical data indicate that tissue engineering could improve the biocompatibility of these novel PPE implants and thus extend their range of clinical applications.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.