ArticleInternational journal of nanomedicine2013
Changes in urinary nanocrystallites in calcium oxalate stone formers before and after potassium citrate intake.
Article in International journal of nanomedicine, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- CarboxymethylatedBiomolecules · 2023Article
- Increased Sulfation inMarine drugs · 2022Article
- In Vitro Studies Reveal Antiurolithic Effect of Antioxidant Sulfated Polysaccharides from the Green SeaweedMarine drugs · 2019Article
- Effects of Calcium Oxalate on Expression of Clusterin and Lower Urinary Tract Symptoms in Prostatitis and Benign Prostatic Hyperplasia Patients with Calculi.Medical science monitor : international medical journal of experimental and clinical research · 2018Article
- Diethyl citrate and sodium citrate reduce the cytotoxic effects of nanosized hydroxyapatite crystals on mouse vascular smooth muscle cells.International journal of nanomedicine · 2017Article
- Nanoparticle Tracking Analysis for the Enumeration and Characterization of Mineralo-Organic Nanoparticles in Feline Urine.PloS one · 2016Article
- Inhibition of urinary macromolecule heparin on aggregation of nano-COM and nano-COD crystals.Molecules (Basel, Switzerland) · 2015Article
- Prophylactic effects of quercetin and hyperoside in a calcium oxalate stone forming rat model.Urolithiasis · 2014Article
- Nanouric acid or nanocalcium phosphate as central nidus to induce calcium oxalate stone formation: a high-resolution transmission electron microscopy study on urinary nanocrystallites.International journal of nanomedicine · 2014Article
- Stabilization of submicron calcium oxalate suspension by chondroitin sulfate C may be an efficient protection from stone formation.Bioinorganic chemistry and applications · 2013Article
- Potassium citrate for stone prevention - Quantifying benefit through the number needed to treat: A narrative review.Urology annalsReview
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6 authors.
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Abstract
The property changes of urinary nanocrystallites in 13 patients with calcium oxalate (CaOx) stones were studied before and after ingestion of potassium citrate (K3cit), a therapeutic drug for stones. The analytical techniques included nanoparticle size analysis, transmission electron microscopy, X-ray diffraction, and Fourier-transform infrared spectroscopy. The studied properties included the components, morphologies, zeta potentials, particle size distributions, light intensity autocorrelation curves, and polydispersity indices (PDIs) of the nanocrystallites. The main components of the urinary nanocrystallites before K3cit intake included uric acid, β-calcium phosphate, and calcium oxalate monohydrate. After K3cit intake, the quantities, species, and percentages of aggregated crystals decreased, whereas the percentages of monosodium urate and calcium oxalate dehydrate increased, and some crystallites became blunt. Moreover, the urinary pH increased from 5.96 ± 0.43 to 6.46 ± 0.50, the crystallite size decreased from 524 ± 320 nm to 354 ± 173 nm, and the zeta potential decreased from -4.85 ± 2.87 mV to -8.77 ± 3.03 mV. The autocorrelation curves became smooth, the decay time decreased from 11.4 ± 3.2 ms to 4.3 ± 1.7 ms, and the PDI decreased from 0.67 ± 0.14 to 0.53 ± 0.19. These changes helped inhibit CaOx calculus formation.
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