ArticleCase reports in nephrology and urology2013
Recurrence of anti-neutrophil cytoplasmic antibody-associated vasculitis in appropriately immunosuppressed renal transplant patients: a discussion of two cases.
Article in Case reports in nephrology and urology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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2 citing papers in PubMed, 4 citations in OpenAlex.
- Orbital Masses in Granulomatosis with Polyangiitis: A Call for Clinical Vigilance.European journal of rheumatology · 2024Article
- Outcome of kidney transplantation in pediatric patients with ANCA-associated glomerulonephritis: a single-center experience.Pediatric nephrology (Berlin, Germany) · 2017Article
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9 authors at 2 institutions in 1 country.
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Abstract
backgroundGranulomatosis with polyangiitis (GPA) (formerly known as Wegener's granulomatosis) is a multisystem autoimmune disease of unknown aetiology. Renal disease manifests as a crescentic glomerulonephritis, with varying degrees of renal failure. Ten percent of patients progress to end-stage kidney disease. Relapse of GPA in renal transplant patients is rare, with a rate of 0.09 relapses per patient per year. PATIENTS AND
methodsWe describe two cases of GPA relapse in immunosuppressed renal transplant patients.
resultsThese patients presented with new-onset graft disfunction, having previously had an uncomplicated posttransplant course. Both patients were on appropriate doses of immunosuppressive agents at the time of relapse, with therapeutic target levels of tacrolimus. We describe the background history and management of both patients.
conclusionThe cases described inform us that although recurrence of anti-neutrophil cytoplasmic antibody vasculitis in transplant patients is rare, it should remain on our list of differential diagnoses in allograft disfunction.
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