Evidence map›Paper›PMID 23467006›Full record

ReviewBiochimica et biophysica acta2014

Open source libraries and frameworks for mass spectrometry based proteomics: a developer's perspective.

Yasset Perez-Riverol, Rui Wang, Henning Hermjakob, Markus Müller, Vladimir Vesada, Juan Antonio Vizcaíno

Abstract readReview
In one paragraph

Review in Biochimica et biophysica acta, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Guideline
  2. Open-Source and FAIR Research Software for Proteomics.Journal of proteome research · 2025
    Review
  3. Review
  4. Article
  5. MS Amanda 2.0: Advancements in the standalone implementation.Rapid communications in mass spectrometry : RCM · 2021
    Article
  6. Review
  7. Review
  8. Clinical Mass Spectrometry in the Bioinformatics Era: A Hitchhiker's Guide.Computational and structural biotechnology journal · 2018
    Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yasset Perez-RiverolEMBL Outstation, European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1SD, UK; Department of Proteomics, Center for Genetic Engineering and Biotechnology, Ciudad de la Habana, Cuba.
Rui Wang
Henning Hermjakob
Markus Müller
Vladimir Vesada
Juan Antonio Vizcaíno

Funding

Biotechnology and Biological Sciences Research CouncilWellcome TrustWellcome Trust WT085949MA
6 · The paper itself

Abstract

Data processing, management and visualization are central and critical components of a state of the art high-throughput mass spectrometry (MS)-based proteomics experiment, and are often some of the most time-consuming steps, especially for labs without much bioinformatics support. The growing interest in the field of proteomics has triggered an increase in the development of new software libraries, including freely available and open-source software. From database search analysis to post-processing of the identification results, even though the objectives of these libraries and packages can vary significantly, they usually share a number of features. Common use cases include the handling of protein and peptide sequences, the parsing of results from various proteomics search engines output files, and the visualization of MS-related information (including mass spectra and chromatograms). In this review, we provide an overview of the existing software libraries, open-source frameworks and also, we give information on some of the freely available applications which make use of them. This article is part of a Special Issue entitled: Computational Proteomics in the Post-Identification Era. Guest Editors: Martin Eisenacher and Christian Stephan.

Indexed as

ProteomicsComputational BiologySoftwareTandem Mass SpectrometryAccurate Mass TagAMTApplication programming interfaceATAQSAutomated and Targeted Analysis with Quantitative SRMBioinformaticsControlled VocabularyCVDAOData Access ObjectDatabasesEBIemPAIEuropean Bioinformatics Instituteexponentially modified Protein Abundance IndexFalse Discovery RateFDRGraphical User InterfaceGUI(Human Proteome Organization) — Proteomics Standards Initiative(HUPO)-PSIICATICPLInstitute for Systems BiologyIPTLISBIsobaric Peptide Termini LabelingIsobaric Tag for Relative and Absolute QuantitationIsotope-Coded Affinity TagsIsotope-Coded Protein LabeliTRAQJava Proteomic LibraryJPLLaboratory Information Management SystemLC-MSLIMSLiquid Chromatography–Mass SpectrometryMascot Generic FormatMass SpectrometryMGFMIAPEMinimum Information About a Proteomics ExperimentMSOpen source softwarePASSELPeptideAtlas SRM Experiment LibraryPeptide Spectrum MatchPost-Translational ModificationsPRIDEProteomicsPRoteomics IDEntifications (database)PSMPTMRetention TimeRTSelected Reaction MonitoringSILACSoftware librariesSRMStable Isotope Labeling by Amino acids in Cell cultureTandem Mass TagThe OpenMS Proteomics PipelineTMTTOPPTPPTrans-Proteomic Pipeline

Identifiers

PMID23467006
PMCPMC3898926

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.