ReviewJournal of innate immunity2013
Neutrophil transmigration: emergence of an adhesive cascade within venular walls.
Review in Journal of innate immunity, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
59 citing papers in PubMed, 107 citations in OpenAlex.
- Effect of Diosmin Administration in Patients with Chronic Venous Disorders on Selected Factors Affecting Angiogenesis.Molecules (Basel, Switzerland) · 2019Trial
- Bleb-based extravasation uses conserved morphodynamics but divergent calcium control.Nature communications · 2026Article
- Advanced Nanoparticle Therapeutics for Targeting Neutrophils in Inflammatory Diseases.Advanced healthcare materials · 2025Review
- Recent advances in the role of neuroregulation in skin wound healing.Burns & trauma · 2025Review
- Basement membranes' role in immune cell recruitment to the central nervous system.Journal of inflammation (London, England) · 2024Article
- Possibility of averting cytokine storm in SARS-COV 2 patients using specialized pro-resolving lipid mediators.Biochemical pharmacology · 2023Review
- Neutrophil breaching of the blood vessel pericyte layer during diapedesis requires mast cell-derived IL-17A.Nature communications · 2022Article
- Temperature-sensitive migration dynamics in neutrophil-differentiated HL-60 cells.Scientific reports · 2022Article
- Review
- Optimal regulation of tumour-associated neutrophils in cancer progression.Royal Society open science · 2022Article
- The Time Course of Monocytes Infiltration After Acoustic Overstimulation.Frontiers in cellular neuroscience · 2022Article
- Role of endothelial cells in graft-versus-host disease.Frontiers in immunology · 2022Review
- Sourcing cells forFrontiers in medical technology · 2022Review
- Atovaquone attenuates experimental colitis by reducing neutrophil infiltration of colonic mucosa.Frontiers in pharmacology · 2022Article
- Article
- Neutrophil-derived granule cargoes: paving the way for tumor growth and progression.Cancer metastasis reviews · 2021Review
- Review
- On the Nonspecific Resistance in Burn Injury: Pathophysiological Aspects (Review).Sovremennye tekhnologii v meditsine · 2021Review
- New Pharmacological Tools to Target Leukocyte Trafficking in Lung Disease.Frontiers in immunology · 2021Review
- Cellular dynamics of myogenic cell migration: molecular mechanisms and implications for skeletal muscle cell therapies.EMBO molecular medicine · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
Abstract
Recruitment of neutrophils from the blood circulation to sites of infection or injury is a key innate immune response against invading pathogens and tissue injury. However, if inappropriately triggered, excessive and/or prolonged, this host defence response can also lead to severe pathological disorders. The migration of all leucocytes out of the vasculature is classically described by the leucocyte adhesion cascade that depicts a well-characterised sequence of cellular and molecular events within the vascular lumen. Recent findings have now illustrated that beyond the vascular lumen, the breaching of the venular wall can also involve an analogous cascade of adhesive events. For neutrophils this involves a tightly regulated and sequential series of responses within venular walls, initiating with adhesive steps that guide neutrophils through endothelial cells lining the venular wall, followed by responses that mediate and regulate their migration through the pericyte sheath and the venular basement membrane. The present review aims to provide a brief summary of novel additions to the classical adhesion cascade within the vascular lumen and then to discuss the emergence of a second adhesion cascade for neutrophils within venular walls, the latter illustrating the intricacies and complexities of neutrophil transmigration.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.