Evidence map›Paper›PMID 23465043›Full record

ArticleJournal of clinical and experimental neuropsychology2013

Prospective memory in HIV-associated neurocognitive disorders (HAND): the neuropsychological dynamics of time monitoring.

Katie L Doyle, Shayne Loft, Erin E Morgan, Erica Weber, Clint Cushman, Elaine Johnston, Igor Grant, Steven Paul Woods, Hiv Neurobehavioral Research Program Hnrp Group

Abstract read
In one paragraph

Article in Journal of clinical and experimental neuropsychology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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  7. Longitudinal declines in event-based, but not time-based, prospective memory among community-dwelling older adults.Neuropsychology, development, and cognition. Section B, Aging, neuropsychology and cognition · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Katie L DoyleDepartment of Psychiatry, University of California, San Diego, CA 92103, USA.
Shayne Loft
Erin E Morgan
Erica Weber
Clint Cushman
Elaine Johnston
Igor Grant
Steven Paul Woods
Hiv Neurobehavioral Research Program Hnrp Group

Funding

STRUCTURAL NEUROIMAGING COREP30MH062512 · NIMH · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Jennifer E Iudicello · 2001 to 2026
$50.4M
Alcohol Research in the Science/Practitioner ModelT32AA013525 · NIAAA · SAN DIEGO STATE UNIVERSITY · PI EDWARD P RILEY, ANDREA SPADONI TOWNSEND · 2002 to 2026
$8.4M
Prospective Memory in HIV-1 InfectionR01MH073419 · NIMH · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI WOODS, STEVEN PAUL · 2005 to 2017
$6.6M
Training in Research on Addictions in Interdisciplinary NeuroAIDS (TRAIN)T32DA031098 · NIDA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Jennifer E Iudicello, DAVID J MOORE · 2011 to 2026
$4.6M
Transnasal Delivery of Chemokine Analogs in mouse NeuroAIDS ModelsR21NS083415 · NINDS · SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE · PI LIPTON, STUART A · 2013 to 2014
$534k
Self-Generation of Prospective Memory in HIV-Infected Methamphetamine UsersF31DA034510 · NIDA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI WEBER, ERICA · 2012 to 2013
$70k
NIAAA NIH HHS T32 AA013525NIAAA NIH HHS T32-AA013525NIDA NIH HHS F31 DA034510NIDA NIH HHS F31-DA034510NIDA NIH HHS T32 DA031098NIDA NIH HHS T32-DA31098NIMH NIH HHS P30 MH062512NIMH NIH HHS P30-MH62512NIMH NIH HHS R01 MH073419NIMH NIH HHS R01-MH073419NINDS NIH HHS R21 NS083415
6 · The paper itself

Abstract

Strategic monitoring during a delay interval is theorized to be an essential feature of time-based prospective memory (TB PM), the cognitive architecture of which is thought to rely heavily on frontostriatal systems and executive functions. This hypothesis was examined in 55 individuals with HIV-associated neurocognitive disorders (HAND) and 108 seronegative comparison participants who were administered the Memory for Intentions Screening Test (MIST), during which time-monitoring (clock-checking) behavior was measured. Results revealed a significant interaction between HAND group and the frequency of clock checking, in which individuals with HAND checked the clock significantly less often than the comparison group across the TB PM retention intervals of the MIST. Subsequent analyses in the HAND sample revealed that the frequency of clocking checking was positively related to overall TB performance, as well as to standard clinical measures of retrospective memory and verbal fluency. These findings add support to a growing body of research elucidating TB PM's reliance on strategic monitoring processes dependent upon intact frontostriatal systems. HIV-associated TB strategic time-monitoring deficits may manifest in poorer functioning outcomes, including medication nonadherence and dependence in activities of daily living. Future research is needed to further delineate the cognitive mechanisms underlying strategic time monitoring in order to advise rehabilitation strategies for reducing HAND-related TB PM deficits.

Indexed as

Memory, EpisodicAdultCognition DisordersExecutive FunctionFemaleHIV InfectionsHumansMaleMiddle AgedNeuropsychological TestsTime Perception

Identifiers

PMID23465043
PMCPMC3631446

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.