ArticleBJOG : an international journal of obstetrics and gynaecology2013
Epidemiological investigation of a temporal increase in atonic postpartum haemorrhage: a population-based retrospective cohort study.
Article in BJOG : an international journal of obstetrics and gynaecology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03069859 (Prophylactic Use of Tranexamic Acid for Preventing Postpartum Hemorrhage), which is not on this map. Cited by 43 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Prophylactic Use of Tranexamic Acid for Preventing Postpartum Hemorrhage: A Randomized, Double-blinded, Placebo-controlled Pilot Trial
Who cites it
43 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Placental Growth Factor as a Prognostic Tool in Women With Hypertensive Disorders of Pregnancy: A Systematic Review.Hypertension (Dallas, Tex. : 1979) · 2017Pooled it
- Maternal, Labor, Delivery, and Perinatal Outcomes Associated with Placental Abruption: A Systematic Review.American journal of perinatology · 2017Pooled it
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- Prolonged second stage of labor and risk of postpartum hemorrhage in nullipara with epidural anesthesia and vaginal delivery: A cohort study with propensity score analysis.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2025Article
- Article
- [Cell salvage in obstetrics-Background and practical implementation].Die Anaesthesiologie · 2024Review
- Association between duration of intrapartum oxytocin exposure and obstetric hemorrhage.Archives of gynecology and obstetrics · 2024Article
- Predictors of Postpartum Hemorrhage and Associated Outcomes at a Midwest Academic Medical Center.Women's health reports (New Rochelle, N.Y.) · 2024Article
- Peripartum Haemorrhage, Diagnosis and Therapy. Guideline of the DGGG, OEGGG and SGGG (S2k, AWMF Registry No. 015-063, August 2022).Geburtshilfe und Frauenheilkunde · 2023Article
- Role of Balloon Tamponade as a Therapeutic Non-Surgical Tool in Controlling Obstetric and Gynecological Hemorrhage in Low-Resource Countries.Journal of obstetrics and gynaecology of India · 2022Review
- A comprehensive digital phenotype for postpartum hemorrhage.Journal of the American Medical Informatics Association : JAMIA · 2022Article
- Risk factors and recurrence of cause-specific postpartum hemorrhage: A population-based study.PloS one · 2022Article
- Literature Review: Physiological Management for Preventing Postpartum Hemorrhage.Healthcare (Basel, Switzerland) · 2021Review
- How to specify healthcare process improvements collaboratively using rapid, remote consensus-building: a framework and a case study of its application.BMC medical research methodology · 2021Article
- Characterising and describing postpartum haemorrhage emergency kits in context: a protocol for a mixed-methods study.BMJ open · 2021Article
- Factors Associated with Failure of Bakri Balloon Tamponade for the Management of Postpartum Haemorrhage. Case Series Study and Systematic Review.Healthcare (Basel, Switzerland) · 2021Article
- Accuracy of postpartum hemorrhage coding in the Swedish Pregnancy Register.Acta obstetricia et gynecologica Scandinavica · 2021Article
- Incidence and Risk Factors of Postpartum Hemorrhage in China: A Multicenter Retrospective Study.Frontiers in medicine · 2021Article
- Incidences of Atonic Postpartum Hemorrhage and Related Risk Factors at a Tertiary Hospital in Saudi Arabia.Nursing reports (Pavia, Italy) · 2020Article
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Authors and funding
6 authors.
Funding
Abstract
objectiveIncreases in atonic postpartum haemorrhage (PPH) have been reported from several countries in recent years. We attempted to determine the potential cause of the increase in atonic and severe atonic PPH.
designPopulation-based retrospective cohort study.
settingBritish Columbia, Canada, 2001-2009. POPULATION: All women with live births or stillbirths.
methodsDetailed clinical information was obtained for 371 193 women from the British Columbia Perinatal Data Registry. Outcomes of interest were atonic PPH and severe atonic PPH (atonic PPH with blood transfusion ≥1 unit; atonic PPH with blood transfusion ≥3 units or procedures to control bleeding), whereas determinants studied included maternal characteristics (e.g. age, parity, and body mass index) and obstetrics practice factors (e.g. labour induction, augmentation, and caesarean delivery). Year-specific unadjusted and adjusted odds ratios for the outcomes were compared using logistic regression.
main outcome measuresAtonic PPH and severe atonic PPH.
resultsAtonic PPH increased from 4.8% in 2001 to 6.3% in 2009, atonic PPH with blood transfusion ≥1 unit increased from 16.6 in 2001 to 25.5 per 10 000 deliveries in 2009, and atonic PPH with blood transfusion ≥3 units or procedures to control bleeding increased from 11.9 to 17.6 per 10 000 deliveries. The crude 34% (95% CI 26-42%) increase in atonic PPH between 2001 and 2009 remained unchanged (42% increase, 95% CI 34-51%) after adjustment for determinants of PPH. Similarly, adjustment did not explain the increase in severe atonic PPH.
conclusionsChanges in maternal characteristics and obstetric practice do not explain the recent increase in atonic and severe atonic PPH.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.