Evidence map›Paper›PMID 23463312›Full record

ReviewNature structural & molecular biology2013

DNA methylation dynamics in health and disease.

Yehudit Bergman, Howard Cedar

Erratum issued Registry-linked trialAbstract readReview
PubMed Publisher
In one paragraph

Review in Nature structural & molecular biology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to trial NCT05772897 (Effects of Attachment-Focused Parenting Intervention on Postpartum Depression and Biological Markers of Stress in Mothers and Their Infants), which is not on this map. Cited by 317 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
317citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05772897 narecruitingnot on this mapstarted 2023, after this paper: background citation

Effects of Attachment-Focused Parenting Intervention on Postpartum Depression and Biological Markers of Stress in Mothers and Their Infants

TypeinterventionalSponsorUniversity of Colorado, DenverRan2023 to 2035Enrolled750ConditionsPostpartum DepressionArmsCircle of Security Parenting program
3 · Its place in the literature

Who cites it

317 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. Article
  6. Toward the simultaneous detection of multiple diseases with a highly cost-effective cell-free DNA methylome test.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  7. Article
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  9. Article
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  11. Article
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  16. A CpG Epigenetic Switch Reverts PFAS ToxicityAn In Vitro Study.Environment & health (Washington, D.C.) · 2025
    Article
  17. Article
  18. Article
  19. Beyond genes: a clinician's guide to epigenetics.Breathe (Sheffield, England) · 2025
    Review
  20. Review

257 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Yehudit BergmanDepartment of Developmental Biology and Cancer Research, Institute for Medical Research Israel-Canada, Hebrew University Medical School, Jerusalem, Israel. yehudit.bergman@huji.ac.il
Howard Cedar

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

DNA methylation is an epigenetic mark that is erased in the early embryo and then re-established at the time of implantation. In this Review, dynamics of DNA methylation during normal development in vivo are discussed, starting from fertilization through embryogenesis and postnatal growth, as well as abnormal methylation changes that occur in cancer.

Indexed as

DNA MethylationGene Expression Regulation, DevelopmentalCpG IslandsEmbryo ImplantationEmbryonic DevelopmentEpigenesis, GeneticHumansNeoplasms

Identifiers

PMID23463312

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.