SynthesisClinical orthopaedics and related research2013
Staphylococcus aureus screening and decolonization in orthopaedic surgery and reduction of surgical site infections.
Synthesis in Clinical orthopaedics and related research, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 63 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
63 citing papers in PubMed, 1 synthesis or guideline pooled it, 198 citations in OpenAlex.
- Can nasal Staphylococcus aureus screening and decolonization prior to elective total joint arthroplasty reduce surgical site and prosthesis-related infections? A systematic review and meta-analysis.Journal of orthopaedic surgery and research · 2020Pooled it
- Bacterial Decolonization for Prevention of Radiation Dermatitis: A Randomized Clinical Trial.JAMA oncology · 2023Trial
- Scaling up Quality Improvement for Surgical Teams (QIST)-avoiding surgical site infection and anaemia at the time of surgery: a cluster randomised controlled trial of the effectiveness of quality improvement collaboratives to introduce change in the NHS.Implementation science : IS · 2022Trial
- Does Preoperative Decolonization Reduce Surgical Site Infections in Elective Orthopaedic Surgery? A Prospective Randomized Controlled Trial.Clinical orthopaedics and related research · 2020Trial
- A tool based on objective data to identify patients at elevated risk of hospital-onsetAntimicrobial stewardship & healthcare epidemiology : ASHE · 2026Article
- Infection prevention strategies in shoulder surgery: A survey of fellowship-trained shoulder surgeons.Shoulder & elbow · 2025Article
- Trends in Complications Following Pediatric Anterior Cruciate Ligament Reconstruction as Reported to the American Board of Orthopaedic Surgery Part II Oral Examination Database.Journal of the Pediatric Orthopaedic Society of North America · 2025Article
- Bacterial Isolates From Orthopedic Posttraumatic Surgical Infections in Northern Ghana: ESInternational journal of microbiology · 2025Article
- [Staphylococcus aureus colonization as a risk factor for acute radiation dermatitis].Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2024Article
- Addition of vancomycin to cefazolin is often unnecessary for preoperative antibiotic prophylaxis during total joint arthroplasties.Arthroplasty (London, England) · 2024Article
- Outpatient Hip and Knee Arthroplasty Can be Safe in Patients With Multiple Medical Comorbidities via Use of Evidence-Based Perioperative Protocols.HSS journal : the musculoskeletal journal of Hospital for Special Surgery · 2024Article
- Evolution of community-associated MRSA: a 20-year genomic and epidemiological study in Region Örebro County, Sweden.Frontiers in microbiology · 2024Article
- Antibiotic-loaded hydroxyapatite scaffolds fabricated fromInternational journal of pharmaceutics: X · 2023Article
- Antibacterial and Antibiofilm Activity of Nanostructured Copper Films Prepared by Ionized Jet Deposition.Antibiotics (Basel, Switzerland) · 2022Article
- Fracture-related infection.Nature reviews. Disease primers · 2022Review
- Multivalent network modifier upregulates bioactivity of multispecies biofilm-resistant polyalkenoate cement.Bioactive materials · 2022Article
- Lack of association of post-discharge prophylactic antibiotics with decreased risk of surgical site infection following spinal fusion.The Journal of antimicrobial chemotherapy · 2022Article
- High Levels of Methicillin-ResistantInfection and drug resistance · 2022Article
- Screening of MRSA colonization in patients undergoing total joint arthroplasty.Journal of infection prevention · 2021Article
- What is the most cost-effective strategy for nasal screening and Staphylococcus aureus decolonization in patients undergoing total hip arthroplasty?BMC musculoskeletal disorders · 2021Article
3 more citing papers are in PubMed but not listed here.
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundStaphylococcus aureus is the most common organism responsible for orthopaedic surgical site infections (SSIs). Patients who are carriers for methicillin-sensitive S. aureus or methicillin-resistant S. aureus (MRSA) have a higher likelihood of having invasive S. aureus infections. Although some have advocated screening for S. aureus and decolonizing it is unclear whether these efforts reduce SSIs. QUESTIONS/PURPOSES: The purposes of this study were to determine (1) whether S. aureus screening and decolonization reduce SSIs in orthopaedic patients and (2) if implementing this protocol is cost-effective.
methodsStudies for this systematic review were identified by searching PubMed, which includes MEDLINE (1946-present), EMBASE.com (1974-present), and the Cochrane Library's (John Wiley & Sons) Cochrane Database of Systematic Reviews (CDSR), Cochrane Central Register of Controlled Trials (CENTRAL), Database of Abstracts of Reviews of Effects (DARE), Health Technology Assessment Database (HTAD), and the NHS Economic Evaluation Database (NHSEED). Comprehensive literature searches were developed using EMTREE, MeSH, and keywords for each of the search concepts of decolonization, MRSA, and orthopedics/orthopedic surgery. Studies published before 1968 were excluded. We analyzed 19 studies examining the ability of the decolonization protocol to reduce SSIs and 10 studies detailing the cost-effectiveness of S. aureus screening and decolonization.
resultsAll 19 studies showed a reduction in SSIs or wound complications by instituting a S. aureus screening and decolonization protocol in elective orthopaedic (total joints, spine, and sports) and trauma patients. The S. aureus screening and decolonization protocol also saved costs in orthopaedic patients when comparing the costs of screening and decolonization with the reduction of SSIs.
conclusionsPreoperative screening and decolonization of S. aureus in orthopaedic patients is a cost-effective means to reduce SSIs. LEVEL OF EVIDENCE: Level IV, systematic review of Level I-IV studies. See the Guidelines for Authors for a complete description of levels of evidence.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.