ReviewCephalalgia : an international journal of headache2013
Gastric stasis in migraineurs: etiology, characteristics, and clinical and therapeutic implications.
Review in Cephalalgia : an international journal of headache, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05685225 (Safety and Efficacy of Naltrexone/Acetaminophen for the Acute Treatment of Migraine), which is not on this map. Cited by 27 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Safety and Efficacy of Naltrexone/Acetaminophen for the Acute Treatment of Migraine: A Single-Site, Phase 2 Randomized Trial
Who cites it
27 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Effects of selected dietary supplements on migraine prophylaxis: A systematic review and dose-response meta-analysis of randomized controlled trials.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025Pooled it
- STOP 301: A Phase 3, open-label study of safety, tolerability, and exploratory efficacy of INP104, Precision Olfactory Delivery (PODHeadache · 2021Trial
- Pharmacokinetics of DFN-15, a Novel Oral Solution of Celecoxib, Versus Celecoxib 400-mg Capsules: A Randomized Crossover Study in Fasting Healthy Volunteers.Clinical drug investigation · 2017Trial
- Trial
- Improved pharmacokinetics of sumatriptan with Breath Powered™ nasal delivery of sumatriptan powder.Headache · 2013Trial
- Gastric emptying times of high-fat, high-carbohydrate and high-protein standard meals using MRI examinations - a contribution to estimating the time since death.International journal of legal medicine · 2026Article
- Integrative Migraine Therapy: From Current Concepts to Future Directions-A Plastic Surgeon's Perspective.Medicina (Kaunas, Lithuania) · 2025Review
- Atzumi for migraine: a new era of needle-free dihydroergotamine delivery.Annals of medicine and surgery (2012) · 2025Article
- Difference in Cyclic Versus Non-cyclic Symptom Patterns in Patients with the Symptoms of Gastroparesis Undergoing Bioelectric Therapy.Digestive diseases and sciences · 2024Article
- Statistically Optimized Polymeric Buccal Films of Eletriptan Hydrobromide and Itopride Hydrochloride: An In Vivo Pharmacokinetic Study.Pharmaceuticals (Basel, Switzerland) · 2023Article
- The Pharmacokinetics of Drugs Delivered to the Upper Nasal Space.Pharmaceutical medicine · 2023Review
- The Upper Nasal Space: Option for Systemic Drug Delivery, Mucosal Vaccines and "Nose-to-Brain".Pharmaceutics · 2023Review
- Headache as a Neurologic Manifestation of Systemic Disease.Current treatment options in neurology · 2022Review
- Article
- Kynurenine Pathway of Tryptophan Metabolism in Migraine and Functional Gastrointestinal Disorders.International journal of molecular sciences · 2021Review
- A link between gastrointestinal disorders and migraine: Insights into the gut-brain connection.Headache · 2021Review
- Consideration of Migraines Among Risk Factors for Postoperative Nausea and Vomiting.Journal of clinical medicine · 2020Article
- Gut-brain Axis and migraine headache: a comprehensive review.The journal of headache and pain · 2020Review
- Migraine, Cyclic Vomiting Syndrome, and Other Gastrointestinal Disorders.Current treatment options in gastroenterology · 2018Review
- Clinical Implications of Associations between Headache and Gastrointestinal Disorders: A Study Using the Hallym Smart Clinical Data Warehouse.Frontiers in neurology · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
backgroundMigraine is a disabling neurological disorder often complicated by gastrointestinal conditions such as gastric stasis. The association between migraine and gastric stasis has received very little attention in the literature, but the existing evidence suggests that they may share a common etiology.
resultsPatients with migraine and those with gastric stasis exhibit abnormal autonomic nervous system function. Furthermore, empirical studies demonstrate that migraineurs experience significant delays in gastric emptying, both during and outside of attacks, when compared to non-migrainous controls.
conclusionMore research is needed to establish the relationship between gastric stasis and migraine burden and to determine the impact of gastric stasis on migraine treatment.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.