Evidence map›Paper›PMID 23463235›Full record

ReviewCellular and molecular life sciences : CMLS2013

Expanding roles for the evolutionarily conserved Dmrt sex transcriptional regulators during embryogenesis.

Eric J Bellefroid, Lucas Leclère, Amandine Saulnier, Marc Keruzore, Maria Sirakov, Michel Vervoort, Sarah De Clercq

Open access · bronzeAbstract readReview
In one paragraph

Review in Cellular and molecular life sciences : CMLS, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed
3.7field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 72 citations in OpenAlex.

  1. Sex Determination in Sponges.Molecular reproduction and development · 2026
    Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Dmrt2 regulates sex-biased neuronal development in the cingulate cortex.Cellular and molecular life sciences : CMLS · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Medaka (Animals : an open access journal from MDPI · 2024
    Article
  11. Article
  12. Article
  13. Article
  14. Identification and functional analysis ofFrontiers in genetics · 2023
    Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 3 countries.

Eric J BellefroidLaboratoire de Génétique du Développement, Institut de Biologie et de Médecine Moléculaires (IBMM), Université Libre de Bruxelles, rue des Profs. Jeener et Brachet 12, 6041, Gosselies, Belgium, ebellefr@ulb.ac.be.
Lucas Leclère
Amandine Saulnier
Marc Keruzore
Maria Sirakov
Michel Vervoort
Sarah De Clercq
Université Libre de Bruxelles · BECentre National de la Recherche Scientifique · FRUniversity of Bergen · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dmrt genes encode a large family of transcription factors characterized by the presence of a DM domain, an unusual zinc finger DNA binding domain. While Dmrt genes are well known for their important role in sexual development in arthropodes, nematodes and vertebrates, several new findings indicate emerging functions of this gene family in other developmental processes. Here, we provide an overview of the evolution, structure and mechanisms of action of Dmrt genes. We summarize recent findings on their function in sexual regulation and discuss more extensively the role played by these proteins in somitogenesis and neural development.

Indexed as

Embryonic DevelopmentEvolution, MolecularGene Expression Regulation, DevelopmentalAnimalsConserved SequenceHumansMeiosisNeurogenesisPhylogenySex DifferentiationSexual DevelopmentSomitesTranscription FactorsDMRT1 proteinTranscription Factors

Identifiers

PMID23463235
PMCPMC11113232
OpenAlexW2086293695

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.