Trial reportBiological psychiatry2013
Monetary reward processing in obese individuals with and without binge eating disorder.
Trial report in Biological psychiatry, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 103 papers, 6 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
103 citing papers in PubMed, 6 syntheses or guidelines pooled it.
- Differentiating the abnormalities of food and monetary reward cue processing associated with overweight/obesity: an ALE meta-analysis.International journal of obesity (2005) · 2026Pooled it
- The effects of neuromodulation interventions on the eating behaviors of patients with eating disorders compared to healthy controls, sham therapies, and other therapeutic approaches: A systematic review.European psychiatry : the journal of the Association of European Psychiatrists · 2025Pooled it
- The influence of stress on the neural underpinnings of disinhibited eating: a systematic review and future directions for research.Reviews in endocrine & metabolic disorders · 2023Pooled it
- Altered anticipatory brain responses in eating disorders: A neuroimaging meta-analysis.European eating disorders review : the journal of the Eating Disorders Association · 2023Pooled it
- Impulsivity and compulsivity in binge eating disorder: A systematic review of behavioral studies.Progress in neuro-psychopharmacology & biological psychiatry · 2021Pooled it
- The anticipation and outcome phases of reward and loss processing: A neuroimaging meta-analysis of the monetary incentive delay task.Human brain mapping · 2018Pooled it
- Cognitive-Behavioral Therapy and Lisdexamfetamine, Alone and Combined, for Binge-Eating Disorder: Secondary Outcomes of a Randomized Controlled Trial.The International journal of eating disorders · 2025Trial
- Cerebellar Stimulation Modulates Reward Processing: A High-definition Transcranial Direct Current Stimulation Study.Cerebellum (London, England) · 2025Trial
- Neural Responses to Auditory Food Stimuli Following Cognitive Behavioral Therapy for Binge-Eating Disorder.The International journal of eating disorders · 2024Trial
- Change in eating-disorder psychopathology network structure in patients with binge-eating disorder: Findings from treatment trial with 12-month follow-up.Journal of consulting and clinical psychology · 2022Trial
- Intra-individual changes in Stroop-related activations linked to cigarette abstinence in adolescent tobacco smokers: Preliminary findings.Drug and alcohol dependence · 2016Trial
- Prior preferences interfere with the associative learning of food values.Communications psychology · 2026Article
- The neurobiology of binge eating disorder: a systematic review of studies using functional magnetic resonance imaging.Reviews in endocrine & metabolic disorders · 2026Review
- Shared Brain factors in eating disorders and obesity: a systematic review of functional near-infrared spectroscopy (fNIRS) studies.Reviews in endocrine & metabolic disorders · 2026Review
- Beyond weight loss: Integrating GLP-1 RA therapies into psychological and behavioral care for obesity and binge eating disorder.Reviews in endocrine & metabolic disorders · 2026Review
- It is a matter of size-manipulating body size with virtual reality modulates reward sensitivity.Scientific reports · 2026Article
- Beyond diagnosis: a network approach to the emotional and control processes involved in the binge eating spectrum disorders.Scientific reports · 2026Article
- An open-label pilot study of psilocybin-assisted therapy for binge eating disorder.Journal of eating disorders · 2026Article
- Prefrontal Cortex Recruitment to Food Stimuli Differs in Overweight/Obesity and Binge Eating Disorder.European eating disorders review : the journal of the Eating Disorders Association · 2026Article
- Distinct attention network topology and dynamics and their relations with pubertal hormones in preadolescent boys and girls with binge eating.Translational psychiatry · 2025Article
43 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
Abstract
backgroundAn important step in obesity research involves identifying neurobiological underpinnings of nonfood reward processing unique to specific subgroups of obese individuals.
methodsNineteen obese individuals seeking treatment for binge eating disorder (BED) were compared with 19 non-BED obese individuals (OB) and 19 lean control subjects (LC) while performing a monetary reward/loss task that parses anticipatory and outcome components during functional magnetic resonance imaging. Differences in regional activation were investigated in BED, OB, and LC groups during reward/loss prospect, anticipation, and notification.
resultsRelative to the LC group, the OB group demonstrated increased ventral striatal and ventromedial prefrontal cortex activity during anticipatory phases. In contrast, the BED group relative to the OB group demonstrated diminished bilateral ventral striatal activity during anticipatory reward/loss processing. No differences were observed between the BED and LC groups in the ventral striatum.
conclusionsHeterogeneity exists among obese individuals with respect to the neural correlates of reward/loss processing. Neural differences in separable groups with obesity suggest that multiple, varying interventions might be important in optimizing prevention and treatment strategies for obesity.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.