ArticleSurgical infections2013
Predictors of sepsis in moderately severely injured patients: an analysis of the National Trauma Data Bank.
Article in Surgical infections, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
33 citing papers in PubMed, 65 citations in OpenAlex.
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- Sex differences in the time trends of sepsis biomarkers following polytrauma.Scientific reports · 2025Article
- Advancements in Trauma-Induced Acute Kidney Injury: Diagnostic and Therapeutic Innovations.Life (Basel, Switzerland) · 2024Review
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- The Road to Sepsis in Geriatric Polytrauma Patients-Can We Forecast Sepsis in Trauma Patients?Journal of clinical medicine · 2024Article
- A biomarker panel of C-reactive protein, procalcitonin and serum amyloid A is a predictor of sepsis in severe trauma patients.Scientific reports · 2024Observational
- Predictors of sepsis in trauma patients: a National Trauma Data Bank analysis.Frontiers in medicine · 2024Article
- Review
- Sex and Gender Differences in Bacterial Infections.Infection and immunity · 2022Review
- Spinal level and cord involvement in the prediction of sepsis development after vertebral fracture repair for traumatic spinal injury.Journal of neurosurgery. Spine · 2022Article
- Female hormones prevent sepsis-induced cardiac dysfunction: an experimental randomized study.Scientific reports · 2022Article
- The Risk Factors for Mortality among Septic Trauma Patients: A Retrospective Cohort Study Using the National Trauma Data Bank.Emergency medicine international · 2022Article
- Article
- Effect of Anti-Inflammatory and Antimicrobial Cosupplementations on Sepsis Prevention in Critically Ill Trauma Patients at High Risk for Sepsis.Frontiers in pharmacology · 2021Article
- Adrenomedullin and Its Possible Role in Improved Survival in Female Patients with Sepsis: A Study in the South East Asian Region.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2020Article
- Vitamin A supplementation boosts control of antibiotic-resistant Salmonella infection in malnourished mice.PLoS neglected tropical diseases · 2020Article
- Trends, Cost, and Mortality From Sepsis After Trauma in the United States: An Evaluation of the National Inpatient Sample of Hospitalizations, 2012-2016.Critical care medicine · 2020Article
- Characteristics and outcomes of acute colitis diagnosed on cross-sectional imaging presenting via the emergency department in an Irish academic medical centre.Irish journal of medical science · 2020Article
Corrections and comments
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Authors and funding
11 authors at 3 institutions in 2 countries.
Funding
Abstract
backgroundPost-traumatic sepsis is a significant cause of in-hospital death. However, socio-demographic and clinical characteristics that may predict sepsis in injured patients are not well known. The objective of this study was to identify risk factors that may be associated with post-traumatic sepsis.
methodsRetrospective analysis of patients in the National Trauma Data Bank for 2007-2008. Patients older than 16 years of age with an Injury Severity Score (ISS) ≥ 9 points were included. Multivariable logistic regression was used to determine association of sepsis with patient (age, gender, ethnicity, and insurance status), injury (mechanism, ISS, injury type, hypotension), and clinical (major surgical procedure, intensive care unit admission) characteristics.
resultsOf a total of 1.3 million patients, 373,370 met the study criteria, and 1.4% developed sepsis, with an associated mortality rate of approximately 20%. Age, male gender, African-American race, hypotension on emergency department presentation, and motor vehicle crash as the injury mechanism were independently associated with post-traumatic sepsis.
conclusionsSocio-demographic and injury factors, such as age, race, hypotension on admission, and severity and mechanism of injury predict post-traumatic sepsis significantly. Further exploration to explain why these patient groups are at increased risk is warranted in order to understand better and potentially prevent this life-threatening complication.
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Registered trials
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