SynthesisPloS one2013
Repeat prostate biopsy strategies after initial negative biopsy: meta-regression comparing cancer detection of transperineal, transrectal saturation and MRI guided biopsy.
Synthesis in PloS one, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.
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Who cites it
27 citing papers in PubMed, 1 synthesis or guideline pooled it.
- NCCN Guidelines Insights: Prostate Cancer Early Detection, Version 2.2016.Journal of the National Comprehensive Cancer Network : JNCCN · 2016Guideline
- Anatomical approach in magnetic resonance imaging and ultrasonography fusion biopsy for prostate cancer detection: a cross-sectional study.BMC urology · 2026Article
- Ultrasound/MRI-targeted biopsy versus saturated trans-rectal ultrasound guided biopsy of prostate in patients with primary negative conventional biopsy and still elevated PSA: a prospective randomized clinical trial.American journal of clinical and experimental urology · 2023Article
- Initial phantom studies for an office-based low-field MR system for prostate biopsy.International journal of computer assisted radiology and surgery · 2021Article
- Magnetic Resonance-Guided Prostate Ablation.Seminars in interventional radiology · 2019Review
- The clinical utility of transperineal template-guided saturation prostate biopsy for risk stratification after transrectal ultrasound-guided biopsy.Investigative and clinical urology · 2019Article
- Fusion prostate biopsy outperforms 12-core systematic prostate biopsy in patients with prior negative systematic biopsy: A multi-institutional analysis.Urologic oncology · 2018Article
- The Cambridge Prognostic Groups for improved prediction of disease mortality at diagnosis in primary non-metastatic prostate cancer: a validation study.BMC medicine · 2018Article
- What is an acceptable false negative rate in the detection of prostate cancer?Translational andrology and urology · 2018Article
- Pathologic correlation of transperineal in-bore 3-Tesla magnetic resonance imaging-guided prostate biopsy samples with radical prostatectomy specimen.Abdominal radiology (New York) · 2017Article
- Magnetic resonance imaging detection of prostate cancer in men with previous negative prostate biopsy.Translational andrology and urology · 2017Review
- Targeted MRI-guided prostate biopsy: are two biopsy cores per MRI-lesion required?European radiology · 2016Article
- The Prostate Health Index adds predictive value to multi-parametric MRI in detecting significant prostate cancers in a repeat biopsy population.Scientific reports · 2016Article
- MRI-Guided Prostate Biopsy of Native and Recurrent Prostate Cancer.Seminars in interventional radiology · 2016Review
- The significance of anterior prostate lesions on multiparametric magnetic resonance imaging in African-American men.Urologic oncology · 2016Article
- Targeted prostate biopsy and MR-guided therapy for prostate cancer.Abdominal radiology (New York) · 2016Review
- Targeted transperineal biopsy of the prostate has limited additional benefit over background cores for larger MRI-identified tumors.World journal of urology · 2016Article
- Prostate MRI - an update for the referring urologist.Central European journal of urology · 2016Review
- Is magnetic resonance/ultrasound fusion prostate biopsy better than systematic prostate biopsy? An updated meta- and trial sequential analysis.Oncotarget · 2015Article
- Transperineal in-bore 3-T MR imaging-guided prostate biopsy: a prospective clinical observational study.Radiology · 2015Observational
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionThere is no consensus on how to investigate men with negative transrectal ultrasound guided prostate biopsy (TRUS-B) but ongoing suspicion of cancer. Three strategies used are transperineal (TP-B), transrectal saturation (TS-B) and MRI-guided biopsy (MRI-B). We compared cancer yields of these strategies.
methodsPapers were identified by search of Pubmed, Embase and Ovid Medline. Included studies investigated biopsy diagnostic yield in men with at least one negative TRUS-B and ongoing suspicion of prostate cancer. Data including age, PSA, number of previous biopsy episodes, number of cores at re-biopsy, cancer yield, and Gleason score of detected cancers were extracted. Meta-regression analyses were used to analyse the data.
resultsForty-six studies were included; 12 of TS-B, 14 of TP-B, and 20 of MRI-B, representing 4,657 patients. Mean patient age, PSA and number of previous biopsy episodes were similar between the strategies. The mean number of biopsy cores obtained by TP-B and TS-B were greater than MRI-B. Cancer detection rates were 30·0%, 36·8%, and 37·6% for TS-B, TP-B, and MRI-B respectively. Meta-regression analysis showed that MRI-B had significantly higher cancer detection than TS-B. There were no significant differences however between MRI-B and TP-B, or TP-B and TS-B. In a sensitivity analysis incorporating number of previous biopsy episodes (36 studies) the difference between MRI-B and TP-B was not maintained resulting in no significant difference in cancer detection between the groups. There were no significant differences in median Gleason scores detected comparing the three strategies.
conclusionsIn the re-biopsy setting, it is unclear which strategy offers the highest cancer detection rate. MRI-B may potentially detect more prostate cancers than other modalities and can achieve this with fewer biopsy cores. However, well-designed prospective studies with standardised outcome measures are needed to accurately compare modalities and define an optimum re-biopsy approach.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.