Evidence map›Paper›PMID 23460366›Full record

ArticleDevelopmental psychobiology2014

Gene-environment interaction between DRD4 7-repeat VNTR and early child-care experiences predicts self-regulation abilities in prekindergarten.

Daniel Berry, Kathleen McCartney, Stephen Petrill, Kirby Deater-Deckard, Clancy Blair

Abstract read
In one paragraph

Article in Developmental psychobiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. DRD4 interacts with adverse life events in predicting maternal sensitivity via emotion regulation.Journal of family psychology : JFP : journal of the Division of Family Psychology of the American Psychological Association (Division 43) · 2018
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Daniel BerryDepartment of Educational Psychology & Beckman Institute, University of Illinois, Urbana-Champaign, Urbana, IL. djberry@illinois.edu.
Kathleen McCartney
Stephen Petrill
Kirby Deater-Deckard
Clancy Blair

Funding

THE NICHD STUDY OF EARLY CHILD CARE--PHASE 3U10HD025451 · NICHD · WELLESLEY COLLEGE · PI MCCARTNEY, KATHLEEN A · 1989 to 2007
$5.0M
NICHD NIH HHS HD25451NICHD NIH HHS U10 HD025451
6 · The paper itself

Abstract

Intervention studies indicate that children's early child-care experiences can be leveraged to foster their development of effective self-regulation skills. It is less clear whether typical child-care experiences play a similar role. In addition, evidence suggests that children with a common variant of the DRD4 gene (48-bp VNTR, 7-repeat) may be more sensitive to their experiences than those without this variant. Using data from the NICHD Study of Early Child Care and Youth Development, we considered the degree to which children's early child-care experiences-quantity, quality, and type-were associated with their attention and self-regulation abilities in prekindergarten, and, in particular, whether these relations were conditional on DRD4 genotype. G × E interactions were evident across multiple neuropsychological and observational measures of children's attention and self-regulation abilities. Across most outcome measures, DRD4 7+ children spending fewer hours in child care showed more effective attention/self-regulation abilities. For those without a copy of the DRD4 7-repeat allele, such associations were typically null. The results for child-care quality and type indicated no interactions with genotype; the main-effect associations were somewhat inconsistent.

Indexed as

Gene-Environment InteractionSocial Control, InformalAllelesAttentionChild BehaviorChild CareChild, PreschoolFemaleGenotypeHumansMalePolymorphism, GeneticPsychology, ChildReceptors, Dopamine D4Tandem Repeat SequencesTemperamentDRD4 protein, humanReceptors, Dopamine D4attentionchild careearly experienceparental care

Identifiers

PMID23460366
PMCPMC8183459

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.