Evidence map›Paper›PMID 23459832›Full record

ArticleJournal of comparative effectiveness research2012

Facilitating comparative effectiveness research in cancer genomics: evaluating stakeholder perceptions of the engagement process.

Patricia A Deverka, Danielle C Lavallee, Priyanka J Desai, Joanne Armstrong, Mark Gorman, Leah Hole-Curry, James O'Leary, B W Ruffner, John Watkins, David L Veenstra and 3 more

Abstract readEvaluation Study
In one paragraph

Article in Journal of comparative effectiveness research, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Optimizing participant and community engagement in cancer genomic sequencing research.Genetics in medicine : official journal of the American College of Medical Genetics · 2025
    Article
  3. Article
  4. Article
  5. Article
  6. Older Adults' Perspectives on Clinical Research: A Focus Group and Survey Study.The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2016
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Patricia A Deverka
Danielle C Lavallee
Priyanka J Desai
Joanne Armstrong
Mark Gorman
Leah Hole-Curry
James O'Leary
B W Ruffner
John Watkins
David L Veenstra
Laurence H Baker
Joseph M Unger
Scott D Ramsey

Funding

SWOG Foreign AccrualsU10CA037429 · NCI · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI BLANKE, CHARLES D., MEYSKENS, FRANK L. · 1985 to 2014
$205.2M
Center for Comparative Effectiveness Research in Cancer Genomics - CANCERGENRC2CA148570 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI RAMSEY, SCOTT D. · 2009 to 2009
$2.0M
Center for Comparative Effectiveness Research in Cancer Genomics - CANCERGENUC2CA148570 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI RAMSEY, SCOTT D. · 2010 to 2010
$2.0M
NCI NIH HHS 5UC2CA148570-02NCI NIH HHS CA37429NCI NIH HHS RC2 CA148570NCI NIH HHS U10 CA037429NCI NIH HHS UC2 CA148570
6 · The paper itself

Abstract

aimsThe Center for Comparative Effectiveness Research in Cancer Genomics completed a 2-year stakeholder-guided process for the prioritization of genomic tests for comparative effectiveness research studies. We sought to evaluate the effectiveness of engagement procedures in achieving project goals and to identify opportunities for future improvements. MATERIALS &

methodsThe evaluation included an online questionnaire, one-on-one telephone interviews and facilitated discussion. Responses to the online questionnaire were tabulated for descriptive purposes, while transcripts from key informant interviews were analyzed using a directed content analysis approach.

resultsA total of 11 out of 13 stakeholders completed both the online questionnaire and interview process, while nine participated in the facilitated discussion. Eighty-nine percent of questionnaire items received overall ratings of agree or strongly agree; 11% of responses were rated as neutral with the exception of a single rating of disagreement with an item regarding the clarity of how stakeholder input was incorporated into project decisions. Recommendations for future improvement included developing standard recruitment practices, role descriptions and processes for improved communication with clinical and comparative effectiveness research investigators.

conclusionsEvaluation of the stakeholder engagement process provided constructive feedback for future improvements and should be routinely conducted to ensure maximal effectiveness of stakeholder involvement.

Indexed as

GenomicsComparative Effectiveness ResearchCooperative BehaviorHumansInterpersonal RelationsNeoplasmsResearch DesignResearch PersonnelSurveys and QuestionnairesUnited States

Identifiers

PMID23459832
PMCPMC3583228

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.