Evidence map›Paper›PMID 23459692›Full record

ArticleAdvanced functional materials2011

Preparation and Characterization of Molecularly Imprinted Polymeric Nanoparticles for Atrial Natriuretic Peptide (ANP).

Chunyan Wang, Mark Howell, Payal Raulji, Yvonne Davis, Subhra Mohapatra

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Advanced functional materials, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
2.3field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 35 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Chunyan WangDepartment of Molecular Medicine, University of South Florida, 12901 Bruce B. Downs Blvd. ; Nanomedicine Research Center, University of South Florida, 12901 Bruce B. Downs Blvd.
Mark Howell
Payal Raulji
Yvonne Davis
Subhra Mohapatra
University of South Florida · US

Funding

An Integrated Nano-Cell Delivery Platform of Theranostics for Lung CancersR01CA152005 · NCI · UNIVERSITY OF SOUTH FLORIDA · PI MOHAPATRA, SHYAM S, MOHAPATRA, SUBHRA · 2010 to 2014
$1.4M
NCI NIH HHS R01 CA152005
6 · The paper itself

Abstract

Natriuretic peptide receptor A (NPRA), the receptor for the cardiac hormone atrial natriuretic peptide (ANP), is expressed abundantly on cancer cells and disruption of ANP-NPRA signaling inhibits tumor burden and metastasis. Since antagonists of NPRA signaling have not provided reproducible results, we reasoned that a synthetic neutralizing antibody to ANP, which has high selectivity and affinity for ANP, could be used to regulate ANP levels and attenuate NPRA signaling. In this study, we prepared molecularly imprinted polymer nanoparticles (MIPNPs) for ANP using a short peptide of ANP as the template and determined their binding affinity and selectivity. The MIPNPs were prepared by precipitation polymerization using NH

Indexed as

ANP-NPRA signalingAtrial natriuretic peptide (ANP)cancermolecularly imprinted polymernatriuretic peptide receptor A (NPRA)

Identifiers

PMID23459692
PMCPMC3583218
OpenAlexW2040580358

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.