Evidence map›Paper›PMID 23459483›Full record

ArticleAntimicrobial agents and chemotherapy2013

Coproduction of 16S rRNA methyltransferase RmtD or RmtG with KPC-2 and CTX-M group extended-spectrum β-lactamases in Klebsiella pneumoniae.

Maria Fernanda C Bueno, Gabriela R Francisco, Jessica A O'Hara, Doroti de Oliveira Garcia, Yohei Doi

Erratum issuedAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 47 papers.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed.

  1. Antibiotic resistance inFrontiers in microbiology · 2026
    Review
  2. Article
  3. Article
  4. Ribosome-targeting antibiotics and resistanceRSC medicinal chemistry · 2023
    Review
  5. Review
  6. Novel Insights intoMicrobiology spectrum · 2022
    Article
  7. Review
  8. Linear plasmids inMicrobial genomics · 2022
    Article
  9. Article
  10. Prevalence of 16S rRNA Methylation Enzyme GeneFrontiers in microbiology · 2021
    Article
  11. Extensively drug-resistant IMP-16-producing Pseudomonas monteilii isolated from cerebrospinal fluid.Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases · 2021
    Article
  12. Review
  13. Article
  14. Article
  15. Molecular Characterization of Multidrug-ResistantAntimicrobial agents and chemotherapy · 2019
    Article
  16. The role of therapy with aminoglycoside in the outcomes of kidney transplant recipients infected with polymyxin- and carbapenem-resistant Enterobacteriaceae.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2019
    Article
  17. Article
  18. Emergence of co-existence of blaFolia microbiologica · 2019
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Maria Fernanda C BuenoEnteric Diseases and Infections by Special Pathogens Laboratory, Instituto Adolfo Lutz, São Paulo, Brazil.
Gabriela R Francisco
Jessica A O'Hara
Doroti de Oliveira Garcia
Yohei Doi

Funding

University of Pittsburgh Clinical and Translational Science InstituteUL1TR000005 · NCATS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI REIS, STEVEN E · 2012 to 2015
$50.8M
Real-Time PCR for Diagnosis of Culture-Negative Bacterial Meningitis in S?o PauloD43TW006592 · FIC · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI HARRISON, LEE H · 2004 to 2013
$1.7M
Multidrug-Resistant Acinetobacter baumanniiK22AI080584 · NIAID · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI DOI, YOHEI · 2009 to 2010
$269k
FIC NIH HHS D43 TW006592FIC NIH HHS D43TW006592NCATS NIH HHS UL1 TR000005NIAID NIH HHS K22 AI080584NIAID NIH HHS K22AI080584
6 · The paper itself

Abstract

Eight Klebsiella pneumoniae clinical strains with high-level aminoglycoside resistance were collected from eight hospitals in São Paulo State, Brazil, in 2010 and 2011. Three of them produced an RmtD group 16S rRNA methyltransferase, RmtD1 or RmtD2. Five strains were found to produce a novel 16S rRNA methyltransferase, designated RmtG, which shared 57 to 58% amino acid identity with RmtD1 and RmtD2. Seven strains coproduced KPC-2 with or without various CTX-M group extended-spectrum β-lactamases, while the remaining strain coproduced CTX-M-2.

Indexed as

Anti-Bacterial AgentsBase Sequencebeta-LactamasesDrug Resistance, Multiple, BacterialHumansIsoenzymesKlebsiella InfectionsKlebsiella pneumoniaeMethyltransferasesMicrobial Sensitivity TestsMolecular Sequence DataPhylogenyRNA, Ribosomal, 16SAnti-Bacterial Agentsbeta-lactamase KPC-2, Klebsiella pneumoniaebeta-LactamasesIsoenzymesMethyltransferasesRNA, Ribosomal, 16S

Identifiers

PMID23459483
PMCPMC3632927

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.