Evidence map›Paper›PMID 23459093›Full record

ArticleCognitive therapy and research2012

The Efficacy of Cognitive Behavioral Therapy: A Review of Meta-analyses.

Stefan G Hofmann, Anu Asnaani, Imke J J Vonk, Alice T Sawyer, Angela Fang

14 registry-linked trialsOpen access · greenAbstract read
In one paragraph

Article in Cognitive therapy and research, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 14 registered trials, which are not on this map. Cited by 951 papers, 16 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
951citing papers in PubMed, 16 pooled it
75.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02278224 nacompletednot on this mapstarted 2013, after this paper: background citation

Rumination Focused Cognitive Behavioral Therapy for Major Depression and Recurrent Depression and Relapse Prevention -a Pragmatic RCT Study in a Danish Psychiatric Outpatient Service

TypeinterventionalSponsorUniversity of CopenhagenRan2013 to 2016Enrolled131ConditionsDepression, Recurrent DepressionArmsGroup based rumination focused CBT, Group based CBT
NCT03272516 nacompletednot on this mapstarted 2017, after this paper: background citation

Mindfulness Based Cognitive Therapy (MBCT) for Primary Care Patients With Mild to Moderate Symptoms of Depression or Anxiety.

TypeinterventionalSponsorUniversity of IcelandRan2017 to 2020Enrolled120ConditionsDepression, AnxietyArmsMindfulness based cognitive therapy (MBCT), Treatment as usual (TAU)
NCT03327038 naunknown statusnot on this mapstarted 2018, after this paper: background citation

Addressing Depression and Anxiety Symptoms in Patients With Inflammatory Bowel Disease (ADAPT-IBD)

TypeinterventionalSponsorMount Sinai Hospital, CanadaRan2018 to 2020Enrolled160ConditionsInflammatory Bowel Diseases, Crohn Disease, Ulcerative Colitis, DepressionArmsWeb-Based Cognitive Behavioral Therapy, Short Questionnaires, Nurse Monitoring, Detailed Questionnaires, Screening Form
NCT03354819 nacompletednot on this mapstarted 2017, after this paper: background citation

Effects of a Modified Mindfulness-based Cognitive Therapy for Family Caregivers of People With Dementia in Stress Reduction: A Randomized Controlled Trial

TypeinterventionalSponsorThe Hong Kong Polytechnic UniversityRan2017 to 2019Enrolled113ConditionsCarer Stress Syndrome, DementiaArmsModified MBCT, SIRE on dementia
NCT04183946 naunknown statusnot on this mapstarted 2020, after this paper: background citation

Willkommen Mutterglück: A Controlled Trial of Internet Based Cognitive Behavioural Therapy (CBT) for Pregnant and Postpartum Women With Depression and Anxiety

TypeinterventionalSponsorUniversity of ZurichRan2020 to 2024Enrolled300ConditionsPrenatal Anxiety, Generalized Anxiety, Postpartum Depression, Major Depressive DisorderArmsOnline Cognitive Behavioural Therapy
NCT04562948 completednot on this mapstarted 2020, after this paper: background citation

Community Applications of the MindShift App

TypeobservationalSponsorUniversity of WindsorRan2020 to 2022Enrolled380ConditionsAnxiety, Depression, Anxiety Generalized, Anxiety Disorders and Symptoms
NCT05157386 active not recruitingnot on this mapstarted 2021, after this paper: background citation

Physical Exercise as Adjunctive Therapy for Affective Disorder and Anxiety - a Retrospective Study of the Braining Project 2017-2020 Regarding Feasibility, Participants and Changes in Symptoms, Function and Physical Parameters

TypeobservationalSponsorRegion StockholmRan2021 to 2025Enrolled50ConditionsDepression, Physical Inactivity, Bipolar Disorder, Anxiety DisordersArmsBraining
NCT05443139 naunknown statusnot on this mapstarted 2022, after this paper: background citation

Well-being Online: Internet-based Self-administered Intervention to Reduce Anxiety and Depression Symptomatology: Randomized Clinical Trial in 7 Countries

TypeinterventionalSponsorUniversidad Internacional de ValenciaRan2022 to 2024Enrolled200ConditionsAnxiety, Depression, Wellbeing, StressArmsWell-being online
NCT06436521 nacompletednot on this mapstarted 2014, after this paper: background citation

The Efficacy of Online Brief Positive Cognitive Behavior Therapy Compared to Traditional Cognitive Behavior Therapy on Improving Well-Being and Goal Attainment in Young Adults

TypeinterventionalSponsorBabes-Bolyai UniversityRan2014 to 2015Enrolled38ConditionsEmotional Distress, Well-Being, Psychological, PerformanceArmsPositive Cognitive Behavioral Therapy, Traditional Cognitive Behavioral Therapy
NCT06926348 narecruitingnot on this mapstarted 2025, after this paper: background citation

Usability, Acceptability, and Preliminary Effectiveness of a Digital Health Technology for Patient Monitoring of Chronic Insomnia Symptoms and the Promotion of Functional Sleep Behaviors: A Randomized Clinical Trial

TypeinterventionalSponsorUniversita di VeronaRan2025 to 2026Enrolled50ConditionsInsomnia Chronic, InsomniaArmsDigital Health Technology for Chronic Insomnia, Treatment as Usual (TAU)
NCT07124598 nacompletednot on this mapstarted 2026, after this paper: background citation

Virtual Intelligence for Transformative Lifestyle Solutions in Pain

TypeinterventionalSponsorMontefiore Medical CenterRan2026 to 2026Enrolled15ConditionsChronic PainArmsVR Headset Device - Meta Quest 3
NCT07255131 narecruitingnot on this mapstarted 2025, after this paper: background citation

The Effectiveness and Efficacy of an Online Group Cognitive Behavioral Psychotherapy in Patients With Cystic Fibrosis and Caregivers in Comparison to Control Groups by the Hellenic Cystic Fibrosis Association A Randomized Controlled Trial

TypeinterventionalSponsorRakitzi, StavroulaRan2025 to 2028Enrolled52ConditionsDepression - Major Depressive Disorder, Anxiety Chronic, Anxiety, Functional OutcomeArmsGroup A An online group cognitive behavioral psychotherapy in 13 sessions via Zoom, Group B An online group supportive psychotherapy in 13 sessions via Zoom, Group C An online group cognitive behavioral psychotherapy in 13 sessions via Zoom, Group D An online group supportive psychotherapy in 13 sessions via Zoom
NCT07388004 narecruitingnot on this mapstarted 2025, after this paper: background citation

Rewiring Expectations and Amplifying Rewards: A Study Protocol for a Randomized Controlled Trial of Mechanism-Based Group Psychotherapy for Major Depressive Disorder

TypeinterventionalSponsorPhilipps University MarburgRan2025 to 2028Enrolled150ConditionsMajor Depressive Disorder (MDD)ArmsExpectation-Focused Psychotherapeutic Intervention, Reward Enhancement and Activation Therapy
NCT07532551 narecruitingnot on this mapstarted 2026, after this paper: background citation

Assessing the Clinical and Cost Effectiveness of Internet-Based Cognitive Behavioural Therapy (iCBT) for Anxiety and Depression in Singapore

TypeinterventionalSponsorNational University of SingaporeRan2026 to 2028Enrolled390ConditionsDepression and/or Anxiety in the Mild-to-moderate Range, Cognitive Behavioral TherapyArmsInternet-delivered cognitive behavioural therapy (iCBT)
3 · Its place in the literature

Who cites it

951 citing papers in PubMed, 16 syntheses or guidelines pooled it, 3,265 citations in OpenAlex.

  1. Pooled it
  2. Cognitive Behavioral Interventions for Children and Adolescents With Overweight or Obesity: A Systematic Review and Component Network Meta-Analysis.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2026
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  9. The Use of Physical Activity in Coping with Test Anxiety Among Students: A Systematic Review.International journal of environmental research and public health · 2025
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  17. Optimizing the Work of Learning for Flourishing: A Randomized Pilot Study of a Digital CBT-Based Intervention in Medical Students.Academic psychiatry : the journal of the American Association of Directors of Psychiatric Residency Training and the Association for Academic Psychiatry · 2026
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891 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Stefan G HofmannBoston University, Boston, MA.
Anu Asnaani
Imke J J Vonk
Alice T Sawyer
Angela Fang
Boston University · US

Funding

D-Cycloserine Enhancement of Exposure in Social PhobiaR01MH078308 · NIMH · BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) · PI HOFMANN, STEFAN G. · 2007 to 2010
$1.3M
1/3-Exposure D-Cycloserine Enhancement and Genetic Modulators in Panic DisorderR01MH081116 · NIMH · BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) · PI OTTO, MICHAEL W. · 2008 to 2012
$1.2M
Social Anxiety Disorder and Emotion RegulationR21MH073937 · NIMH · GEORGE MASON UNIVERSITY · PI KASHDAN, TODD B · 2006 to 2007
$337k
NIMH NIH HHS R01 MH078308NIMH NIH HHS R01 MH081116NIMH NIH HHS R21 MH073937
6 · The paper itself

Abstract

Cognitive behavioral therapy (CBT) refers to a popular therapeutic approach that has been applied to a variety of problems. The goal of this review was to provide a comprehensive survey of meta-analyses examining the efficacy of CBT. We identified 269 meta-analytic studies and reviewed of those a representative sample of 106 meta-analyses examining CBT for the following problems: substance use disorder, schizophrenia and other psychotic disorders, depression and dysthymia, bipolar disorder, anxiety disorders, somatoform disorders, eating disorders, insomnia, personality disorders, anger and aggression, criminal behaviors, general stress, distress due to general medical conditions, chronic pain and fatigue, distress related to pregnancy complications and female hormonal conditions. Additional meta-analytic reviews examined the efficacy of CBT for various problems in children and elderly adults. The strongest support exists for CBT of anxiety disorders, somatoform disorders, bulimia, anger control problems, and general stress. Eleven studies compared response rates between CBT and other treatments or control conditions. CBT showed higher response rates than the comparison conditions in 7 of these reviews and only one review reported that CBT had lower response rates than comparison treatments. In general, the evidence-base of CBT is very strong. However, additional research is needed to examine the efficacy of CBT for randomized-controlled studies. Moreover, except for children and elderly populations, no meta-analytic studies of CBT have been reported on specific subgroups, such as ethnic minorities and low income samples.

Indexed as

CBTcomprehensive reviewefficacymeta-analyses

Identifiers

PMID23459093
PMCPMC3584580
OpenAlexW2036735145

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

and 8 more above

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.