Evidence map›Paper›PMID 23458627›Full record

ArticlePhysiology & behavior2013

Appetitive traits from infancy to adolescence: using behavioral and neural measures to investigate obesity risk.

Susan Carnell, Leora Benson, Katherine Pryor, Elissa Driggin

Open access · greenAbstract read
In one paragraph

Article in Physiology & behavior, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 65 papers.

0numbers the graph read from it
0cells of the map it votes in
65citing papers in PubMed
3.6field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

65 citing papers in PubMed, 113 citations in OpenAlex.

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  10. Structural and Functional Brain Changes in Children and Adolescents With Obesity.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2025
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5 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 1 country.

Susan CarnellNew York Obesity Nutrition Research Center, St Luke's-Roosevelt Hospital, Columbia University College of Physicians & Surgeons, Babcock Building, Suite 10A, 1111 Amsterdam Avenue, New York, NY 10025, USA. Electronic address: sc2902@columbia.edu.
Leora Benson
Katherine Pryor
Elissa Driggin
Columbia University · USCornell University · USDuke University · USSt. Luke's-Roosevelt Hospital Center · US

Funding

Brain activation to food stimuli in obese and lean adolescents with high and lowK99DK088360 · NIDDK · ST. LUKE'S-ROOSEVELT INST FOR HLTH SCIS · PI CARNELL, SUSAN · 2010 to 2011
$178k
NIDDK NIH HHS K99 DK088360NIDDK NIH HHS K99DK088360
6 · The paper itself

Abstract

We come into the world with enduring predispositions towards food, which interact with environmental factors to influence our eating behaviors and weight trajectories. But our fates are not sealed - by learning more about this process we can identify ways to intervene. To advance this goal this we need to be able to assess appetitive traits such as food cue responsiveness and satiety sensitivity at different developmental stages. Assessment methods might include behavioral measures (e.g. eating behavior tests, psychometric questionnaires), but also biomarkers such as brain responses to food cues measured using fMRI. Evidence from infants, children and adolescents suggests that these indices of appetite differ not only with body weight, but also with familial obesity risk as assessed by parent weight, which reflects both genetic and environmental influences, and may provide a useful predictor of obesity development. Behavioral and neural approaches have great potential to inform each other: examining eating behavior can help us identify meaningful appetitive endophenotypes whose neural bases can be probed, while increasing knowledge of the shared neurobiology underlying appetite, obesity, and related behaviors and disorders may ultimately lead to innovative generalized interventions. Another challenge will be to combine comprehensive behavioral and neural assessments of appetitive traits with measures of relevant genetic and environmental factors within long-term prospective studies. This approach may help to identify the biobehavioral precursors of obesity, and lay the foundations for targeted neurobehavioral interventions that can interrupt the pathway to excess weight.

Indexed as

AppetiteObesityAdolescentAge FactorsBrainCausalityChildChild, PreschoolCuesFeeding BehaviorHumansInfantMagnetic Resonance ImagingOxygenSurveys and QuestionnairesOxygenExternal eatingGenetic obesity riskHigh-riskMaternal obesityNeuroimagingParental obesityReview

Identifiers

PMID23458627
PMCPMC3725261
OpenAlexW2004477749

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.