Evidence map›Paper›PMID 23458424›Full record

SynthesisHPB : the official journal of the International Hepato Pancreato Biliary Association2013

A systematic review of outcomes in patients undergoing liver surgery in an enhanced recovery after surgery pathways.

Mariëlle M E Coolsen, Edgar M Wong-Lun-Hing, Ronald M van Dam, Aart A van der Wilt, Karem Slim, Kristoffer Lassen, Cornelis H C Dejong

Open access · greenAbstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in HPB : the official journal of the International Hepato Pancreato Biliary Association, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers, 13 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
67citing papers in PubMed, 13 pooled it
11.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

67 citing papers in PubMed, 13 syntheses or guidelines pooled it, 134 citations in OpenAlex.

  1. Pooled it
  2. [Enhanced recovery after surgery-Does the ERAS concept keep its promises].Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen · 2021
    Pooled it
  3. Enhanced Recovery After Surgery (ERAS) Reduces Hospital Costs and Improve Clinical Outcomes in Liver Surgery: a Systematic Review and Meta-Analysis.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2020
    Pooled it
  4. ESPEN guideline on clinical nutrition in liver disease.Clinical nutrition (Edinburgh, Scotland) · 2019
    Guideline
  5. Meta-Analysis of Enhanced Recovery Protocols in Bariatric Surgery.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2018
    Pooled it
  6. Pooled it
  7. Enhanced Recovery after Surgery Programs for Liver Resection: a Meta-analysis.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2017
    Pooled it
  8. Pooled it
  9. Central venous pressure and liver resection: a systematic review and meta-analysis.HPB : the official journal of the International Hepato Pancreato Biliary Association · 2015
    Pooled it
  10. Fast-Track Programs for Liver Surgery: A Meta-Analysis.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2015
    Pooled it
  11. Pooled it
  12. Enhanced recovery following liver surgery: a systematic review and meta-analysis.HPB : the official journal of the International Hepato Pancreato Biliary Association · 2014
    Pooled it
  13. Pooled it
  14. Trial
  15. Use of Activity Tracking in Major Visceral Surgery-the Enhanced Perioperative Mobilization Trial: a Randomized Controlled Trial.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2019
    Trial
  16. Trial
  17. Trial
  18. Article
  19. Article
  20. Article

7 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 4 countries.

Mariëlle M E CoolsenDepartment of Surgery, University Hospital Maastricht, Maastricht 6202 AZ, the Netherlands. marielle.coolsen@maastrichtuniversity.nl
Edgar M Wong-Lun-Hing
Ronald M van Dam
Aart A van der Wilt
Karem Slim
Kristoffer Lassen
Cornelis H C Dejong
Maastricht University Medical Centre · NLCentre Hospitalier Universitaire de Clermont-Ferrand · FRUniversity Hospital of North Norway · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesEnhanced recovery after surgery (ERAS) or fast-track protocols have been implemented in different fields of surgery to attenuate the surgical stress response and accelerate recovery. The objective of this study was to systematically review the literature on outcomes of ERAS protocols applied in liver surgery.

methodsThe MEDLINE, EMBASE, PubMed and Cochrane Library databases were searched for randomized controlled trials (RCTs), case-control studies and case series published between January 1966 and October 2011 comparing adult patients undergoing elective liver surgery in an ERAS programme with those treated in a conventional manner. The primary outcome measure was hospital length of stay (LoS). Secondary outcome measures were time to functional recovery, and complication, readmission and mortality rates.

resultsA total of 307 articles were found, six of which were included in the review. These comprised two RCTs, three case-control studies and one retrospective case series. Median LoS ranged from 4 days in an ERAS group to 11 days in a control group. Morbidity, mortality and readmission rates did not differ significantly between the groups. Only two studies assessed time to functional recovery. Functional recovery in these studies was reached 2 days before discharge.

conclusionsThis systematic review suggests that ERAS protocols can be successfully implemented in liver surgery. Length of stay is reduced without compromising morbidity, mortality or readmission rates.

Indexed as

Length of StayCritical PathwaysElective Surgical ProceduresEvidence-Based MedicineHumansLiver DiseasesNetherlandsOutcome Assessment, Health CarePatient ReadmissionRandomized Controlled Trials as TopicRecovery of FunctionSurvival RateTreatment Outcome

Identifiers

PMID23458424
PMCPMC3608977
OpenAlexW2086415921

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.