Evidence map›Paper›PMID 23457772›Full record

ArticleBiochemia medica2013

Hepatitis during respiratory syncytial virus infection--a case report.

Branka Kristić Kirin, Renata Zrinski Topić, Slavica Dodig

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Biochemia medica, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Hepatic involvement in major respiratory viral infections.Clinical and experimental hepatology · 2025
    Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. [The investigation on the acute, severe hepatitis of unknown origin in children].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2022
    Article
  10. Article
  11. Article
  12. Neurologic Alterations Due to Respiratory Virus Infections.Frontiers in cellular neuroscience · 2018
    Review
  13. Review
  14. Article
  15. Human Respiratory Syncytial Virus: Infection and Pathology.Seminars in respiratory and critical care medicine · 2016
    Review
  16. Article
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Branka Kristić KirinDaily Hospital, Srebrnjak Children's Hospital, Zagreb, Croatia.
Renata Zrinski Topić
Slavica Dodig
Children's Hospital Zagreb · HRChildren's Hospital Srebrnjak · HR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionRespiratory syncytial virus (RSV) infection is the most common cause of hospitalization in infants and small children. The aim was to present a 13-months old boy diagnosed with acute airway infection, acute otitis media (AOM) and hepatitis during the RSV-infection. MATERIAL AND

methodsSerum catalytic activities of alkaline phosphatase (ALP), aspartate aminotranspherase (AST), alanine aminotranspherase (ALT), gamma glutamyl transpherase (GGT), lactate dehydrogenase (LD), and concentrations of bilirubin were monitored during hospitalization and at control examination.

resultsThe child had clinical signs and symptoms of respiratory failure, AOM, and laboratory findings of virus infection and liver disease. On admission, catalytic activities of enzymes were markedly increased, especially the activity of ALP (10333 U/L, i.e. 24-fold increase in comparison with the upper reference limit). The highest increased in AST (339 U/L, 4.5-fold), ALT (475 U/L, 10.3-fold) and LD (545 U/L, 1.5-fold) were registered on the 3rd day, and the highest increase in GGT (68 U/L, 3.1-fold) occurred on the 11th day. Seven weeks after discharge AST, ALT, GGT and LD decreased into reference range, and ALP remain mildly increased (478 U/L, 1.1 fold increase). RSV was confirmed in nasal lavage fluid.

conclusionLaboratory results in patient with RSV infection needs to be interpreted in the light of both, respiratory and extrapulmonary manifestations of the infection, respectively.

Indexed as

Alanine TransaminaseAlkaline PhosphataseAspartate AminotransferasesBiomarkersHepatitisHumansInfantL-Lactate DehydrogenaseMaleOtitis MediaPrognosisRespiratory Syncytial VirusesRespiratory Syncytial Virus InfectionsAlanine TransaminaseAlkaline PhosphataseAspartate AminotransferasesBiomarkersL-Lactate Dehydrogenase

Identifiers

PMID23457772
PMCPMC3900097
OpenAlexW2125569187

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.