ArticleGenetics2013
Intragenomic conflict between the two major knob repeats of maize.
Article in Genetics, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
27 citing papers in PubMed, 40 citations in OpenAlex.
- Article
- Genetic and environmental influences on the distributions of three chromosomal drive haplotypes in maize.PLoS genetics · 2025Article
- Review
- The maize abnormal chromosome 10 meiotic drive haplotype: a review.Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology · 2022Review
- Intragenomic Conflict between Knob Heterochromatin and B Chromosomes Is the Key to Understand Genome Size Variation along Altitudinal Clines in Maize.Plants (Basel, Switzerland) · 2021Article
- Mechanisms of meiotic drive in symmetric and asymmetric meiosis.Cellular and molecular life sciences : CMLS · 2021Review
- European maize genomes highlight intraspecies variation in repeat and gene content.Nature genetics · 2020Article
- Mixed knobs in corn cobs.Genes & development · 2020Review
- Distinct kinesin motors drive two types of maize neocentromeres.Genes & development · 2020Article
- Genetic and epigenetic effects on centromere establishment.Chromosoma · 2020Review
- Recurrent Amplification of the Heterochromatin Protein 1 (HP1) Gene Family across Diptera.Molecular biology and evolution · 2018Article
- The cellular mechanisms and consequences of centromere drive.Current opinion in cell biology · 2018Review
- Parallel altitudinal clines reveal trends in adaptive evolution of genome size in Zea mays.PLoS genetics · 2018Article
- Modeling the Evolution of Female Meiotic Drive in Maize.G3 (Bethesda, Md.) · 2018Article
- Exploring karyotype diversity of Argentinian Guaraní maize landraces: Relationship among South American maize.PloS one · 2018Article
- Fitness Costs and Variation in Transmission Distortion Associated with the Abnormal Chromosome 10 Meiotic Drive System in Maize.Genetics · 2018Article
- Recurrent Innovation at Genes Required for Telomere Integrity in Drosophila.Molecular biology and evolution · 2017Article
- Gametocidal Factor Transferred fromFrontiers in plant science · 2017Article
- Marcus Rhoades on Preferential Segregation in Maize.Genetics · 2016Article
- Pollen Killer Gene S35 Function Requires Interaction with an Activator That Maps Close to S24, Another Pollen Killer Gene in Rice.G3 (Bethesda, Md.) · 2016Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Examples of meiotic drive, the non-Mendelian segregation of a specific genomic region, have been identified in several eukaryotic species. Maize contains the abnormal chromosome 10 (Ab10) drive system that transforms typically inert heterochromatic knobs into centromere-like domains (neocentromeres) that move rapidly poleward along the spindle during meiosis. Knobs can be made of two different tandem repeat sequences (TR-1 and 180-bp repeat), and both repeats have become widespread in Zea species. Here we describe detailed studies of a large knob on chromosome 10 called K10L2. We show that the knob is composed entirely of the TR-1 repeat and is linked to a strong activator of TR-1 neocentromere activity. K10L2 shows weak meiotic drive when paired with N10 but significantly reduces the meiotic drive exhibited by Ab10 (types I or II) in Ab10/K10L2 heterozygotes. These and other data confirm that (1) there are two separate and independent neocentromere activities in maize, (2) that both the TR-1 and knob 180 repeats exhibit meiotic drive (in the presence of other drive genes), and (3) that the two repeats can operate in competition with each other. Our results support the general concept that tandem repeat arrays can engage in arms-race-like struggles and proliferate as an outcome.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.