Evidence map›Paper›PMID 23457213›Full record

Trial reportBMJ (Clinical research ed.)2013

Promotion of physical activity and fitness in sedentary patients with Parkinson's disease: randomised controlled trial.

Marlies van Nimwegen, Arlène D Speelman, Sebastiaan Overeem, Bart P van de Warrenburg, Katrijn Smulders, Manon L Dontje, George F Borm, Frank J G Backx, Bastiaan R Bloem, Marten Munneke and 1 more

2 registry-linked trialsOpen access · hybridAbstract readMulticenter StudyRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in BMJ (Clinical research ed.), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 60 papers, 10 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
60citing papers in PubMed, 10 pooled it
20.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00748488 phase3completednot on this map

The ParkFit Study; Effectiveness of an Active Lifestyle Promotion Program for Patients With Parkinson's Disease

TypeinterventionalSponsorRadboud University Medical CenterRan2008 to 2011Enrolled700ConditionsParkinson's DiseaseArmsPhysical therapy aimed to move safely, Physical Therapy aimed to improve Physical Activity
NCT03517371 nacompletednot on this mapstarted 2019, after this paper: background citation

Walking and mHealth to Increase Participation in Parkinson Disease

TypeinterventionalSponsorBoston University Charles River CampusRan2019 to 2024Enrolled140ConditionsParkinson DiseaseArmsmHealth delivered exercise program, Exercise only
3 · Its place in the literature

Who cites it

60 citing papers in PubMed, 10 syntheses or guidelines pooled it, 167 citations in OpenAlex.

  1. Pooled it
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  5. Interventions for preventing falls in Parkinson's disease.The Cochrane database of systematic reviews · 2022
    Pooled it
  6. Guideline
  7. Occupational Therapy Interventions for Instrumental Activities of Daily Living for Adults With Parkinson's Disease: A Systematic Review.The American journal of occupational therapy : official publication of the American Occupational Therapy Association · 2021
    Pooled it
  8. Pooled it
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  10. Virtual reality for rehabilitation in Parkinson's disease.The Cochrane database of systematic reviews · 2016
    Pooled it
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Marlies van NimwegenDepartment of Neurology, Radboud University Nijmegen Medical Centre, Nijmegen Centre for Evidence Based Practice, Nijmegen, Netherlands.
Arlène D Speelman
Sebastiaan Overeem
Bart P van de Warrenburg
Katrijn Smulders
Manon L Dontje
George F Borm
Frank J G Backx
Bastiaan R Bloem
Marten Munneke
ParkFit Study Group
Radboud University Nijmegen · NLRadboud University Medical Center · NLUniversity Medical Center Groningen · NLUniversity Medical Center Utrecht · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate whether a multifaceted behavioural change programme increases physical activities in patients with Parkinson's disease.

designMulticentre randomised controlled trial.

setting32 community hospitals in the Netherlands, collaborating in a nationwide network (ParkinsonNet).

participants586 sedentary patients with idiopathic Parkinson's disease aged between 40 and 75 years with mild to moderate disease severity (Hoehn and Yahr stage ≤ 3).

interventionPatients were randomly assigned to the ParkFit programme or a matched general physiotherapy intervention. ParkFit is a multifaceted behavioural change programme, designed specifically to achieve an enduring increase in the level of physical activity (coaches using motivational strategies; ambulatory feedback).

main outcome measuresThe primary endpoint was the level of physical activity, measured every six months with a standardised seven day recall (LASA physical activity questionnaire-LAPAQ). Secondary endpoints included two other measures of physical activity (activity diary and ambulatory activity monitor), quality of life (Parkinson's disease questionnaire-PDQ-39), and fitness (six minute walk test).

results540 (92.2%) patients completed the primary outcome. During follow-up, overall time spent on physical activities (LAPAQ) was comparable between the groups (adjusted group difference 7%, 95% confidence interval -3 to 17%; P=0.19). Analyses of three secondary outcomes indicated increased physical activity in ParkFit patients, as suggested by the activity diary (difference 30%; P<0.001), the activity monitor (difference 12%; P<0.001), and the six minute walk test (difference 4.8 m; P=0.05). PDQ-39 did not differ between ParkFit patients and controls (difference -0.9 points; P=0.14). The number of fallers was comparable between ParkFit patients (184/299; 62%) and controls (191/287; 67%).

conclusionsThe ParkFit behavioural change programme did not increase overall physical activity, as measured with the LAPAQ. The analysis of the secondary endpoints justifies further work into the possible merits of behavioural change programmes to increase physical activities in daily life in Parkinson's disease.

trial registrationClinical trials NCT00748488.

Indexed as

Health BehaviorMotor ActivitySedentary BehaviorAccidental FallsAdultAgedExercise TestFemaleHumansMaleMiddle AgedParkinson DiseaseSeverity of Illness IndexSurveys and Questionnaires

Identifiers

PMID23457213
PMCPMC3585777
OpenAlexW2011174050

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.