ReviewSports medicine (Auckland, N.Z.)2013
Corticospinal responses to sustained locomotor exercises: moving beyond single-joint studies of central fatigue.
Review in Sports medicine (Auckland, N.Z.), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
31 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- The Role of Muscle Mass in Endurance Performance and Neuromuscular Fatigue: A Systematic Review and Meta-Analysis.Sports medicine (Auckland, N.Z.) · 2025Pooled it
- Is tDCS an Adjunct Ergogenic Resource for Improving Muscular Strength and Endurance Performance? A Systematic Review.Frontiers in psychology · 2019Pooled it
- Anodal tDCS improves neuromuscular adaptations to short-term resistance training of the knee extensors in healthy individuals.Journal of neurophysiology · 2024Trial
- Computational signatures of exertion and rest underlie moment-to-moment dynamics of subjective perceptions of effort and fatigue.Cognitive, affective & behavioral neuroscience · 2026Article
- Increasing the cognitive demand of upper-limb psychomotor tasks increases the perception of effort.Cognitive, affective & behavioral neuroscience · 2026Article
- Contraction intensity modulates spinal excitability during transcranial magnetic stimulation-evoked silent period in rectus femoris muscle.European journal of applied physiology · 2024Article
- Test-retest reliability of cortico-spinal measurements in the rectus femoris at different contraction levels.Frontiers in neuroscience · 2023Article
- Potential physiological responses contributing to the ergogenic effects of acute ischemic preconditioning during exercise: A narrative review.Frontiers in physiology · 2022Review
- Transcranial Direct Current Stimulation Enhances Exercise Performance: A Mini Review of the Underlying Mechanisms.Frontiers in neuroergonomics · 2022Review
- Perception of effort and the allocation of physical resources: A generalization to upper-limb motor tasks.Frontiers in psychology · 2022Article
- Corticospinal Excitability Is Lower During Eccentric Than Concentric Cycling in Men.Frontiers in physiology · 2022Article
- Locomotor activities as a way of inducing neuroplasticity: insights from conventional approaches and perspectives on eccentric exercises.European journal of applied physiology · 2021Review
- Single joint fatiguing exercise decreases long but not short-interval intracortical inhibition in older adults.Experimental brain research · 2021Article
- Sustained Isometric Wrist Flexion and Extension Maximal Voluntary Contractions on Corticospinal Excitability to Forearm Muscles during Low-Intensity Hand-Gripping.Brain sciences · 2020Article
- Article
- Global Corticospinal Excitability as Assessed in A Non-Exercised Upper Limb Muscle Compared Between Concentric and Eccentric Modes of Leg Cycling.Scientific reports · 2019Article
- Dietary Nitrate Supplementation Improves Exercise Tolerance by Reducing Muscle Fatigue and Perceptual Responses.Frontiers in physiology · 2019Article
- High-intensity exhaustive exercise reduces long-interval intracortical inhibition.Experimental brain research · 2018Article
- Fatigue-related group III/IV muscle afferent feedback facilitates intracortical inhibition during locomotor exercise.The Journal of physiology · 2018Article
- Performance Fatigability: Mechanisms and Task Specificity.Cold Spring Harbor perspectives in medicine · 2018Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
There is substantial evidence that fatiguing exercise is accompanied by changes within the central nervous system that reduce the force that can be produced by working muscles. Here we review studies that used non-invasive neurophysiological techniques to show that sustained single-joint contractions have the capacity to increase corticospinal responsiveness and reduce motoneuronal responsiveness. We contrast these findings with new evidence from our laboratory regarding corticospinal responsiveness during sustained cycling exercise. There seems to be a similar increase in responsiveness of the intracortical inhibitory interneurons during sustained locomotor and single-joint exercise which might be due to acute exercise responses that are common to fatiguing exercise of any nature, such as local accumulation of fatigue metabolites. In contrast, the pattern of changes in corticospinal responsiveness is fundamentally different between the two modes of exercise which might be due to greater systemic fatigue responses to locomotor exercises.
Indexed as
Identifiers
23456490What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.