Evidence map›Paper›PMID 23456424›Full record

ReviewLangenbeck's archives of surgery2013

German Association of Endocrine Surgeons practice guideline for the surgical management of malignant thyroid tumors.

Henning Dralle, Thomas J Musholt, Jochen Schabram, Thomas Steinmüller, Andreja Frilling, Dietmar Simon, Peter E Goretzki, Bruno Niederle, Christian Scheuba, Thomas Clerici and 17 more

Abstract readReview
PubMed Publisher
In one paragraph

Review in Langenbeck's archives of surgery, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 101 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
101citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

101 citing papers in PubMed, 5 syntheses or guidelines pooled it.

  1. Guideline
  2. Completion Thyroidectomy Trends and Rates: A Systematic Review and Meta-Analysis.Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery · 2025
    Pooled it
  3. Guideline
  4. Differentiated Thyroid Cancer-Treatment: State of the Art.International journal of molecular sciences · 2017
    Pooled it
  5. Pooled it
  6. Trial
  7. Trial
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Case Series of Surgical Treatment in Pediatric Thyroid Carcinoma in a Single Institution.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2024
    Article
  20. Review

41 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

27 authors.

Henning DralleDepartment of General, Visceral and Vascular Surgery, Martin Luther University Halle-Wittenberg, Ernst-Grube-Straße 40, 06097, Halle, Saale, Germany. henning.dralle@uk-halle.de
Thomas J Musholt
Jochen Schabram
Thomas Steinmüller
Andreja Frilling
Dietmar Simon
Peter E Goretzki
Bruno Niederle
Christian Scheuba
Thomas Clerici
Michael Hermann
Jochen Kußmann
Kerstin Lorenz
Christoph Nies
Peter Schabram
Arnold Trupka
Andreas Zielke
Wolfram Karges
Markus Luster
Kurt W Schmid
Dirk Vordermark
Hans-Joachim Schmoll
Reinhard Mühlenberg
Otmar Schober
Harald Rimmele
Andreas Machens
German Societies of General and Visceral Surgery; Endocrinology; Nuclear Medicine; Pathology; Radiooncology; Oncological Hematology; and the German Thyroid Cancer Patient Support Organization Ohne Schilddrüse leben e.V

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionOver the past years, the incidence of thyroid cancer has surged not only in Germany but also in other countries of the Western hemisphere. This surge was first and foremost due to an increase of prognostically favorable ("low risk") papillary thyroid microcarcinomas, for which limited surgical procedures are often sufficient without loss of oncological benefit. These developments called for an update of the previous practice guideline to detail the surgical treatment options that are available for the various disease entities and tumor stages.

methodsThe present German Association of Endocrine Surgeons practice guideline was developed on the basis of clinical evidence considering current national and international treatment recommendations through a formal expert consensus process in collaboration with the German Societies of General and Visceral Surgery, Endocrinology, Nuclear Medicine, Pathology, Radiooncology, Oncological Hematology, and a German thyroid cancer patient support organization.

resultsThe practice guideline for the surgical management of malignant thyroid tumors includes recommendations regarding preoperative workup; classification of locoregional nodes and terminology of surgical procedures; frequency, clinical, and histopathological features of occult and clinically apparent papillary, follicular, poorly differentiated, undifferentiated, and sporadic and hereditary medullary thyroid cancers, thyroid lymphoma and thyroid metastases from primaries outside the thyroid gland; extent of thyroidectomy; extent of lymph node dissection; aerodigestive tract resection; postoperative follow-up and surgery for recurrence and distant metastases.

conclusionThese evidence-based recommendations for surgical therapy reflect various "treatment corridors" that are best discussed within multidisciplinary teams and the patient considering tumor type, stage, progression, and inherent surgical risk.

Indexed as

Practice Guidelines as TopicEndocrine Surgical ProceduresGermanyGuideline AdherenceHumansLymph Node ExcisionLymph NodesNeoplasm StagingSocieties, MedicalThyroidectomyThyroid NeoplasmsTreatment Outcome

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.