ArticleInternational journal of clinical oncology2014
Clinicopathological correlation for the role of fluorodeoxyglucose positron emission tomography computed tomography in detection of choroidal malignant melanoma.
Article in International journal of clinical oncology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 17 citations in OpenAlex.
- Article
- Advances in Positron Emission Tomography/Computed Tomography for Diagnosing and Managing Primary Posterior Uveal Melanoma.Medical science monitor : international medical journal of experimental and clinical research · 2025Review
- Article
- Local Control of Conjunctival Malignant Melanoma by Proton Beam Therapy in a Patient With No Metastasis in Six Years FromJournal of medical cases · 2025Article
- Review
- Review
- Non-Cutaneous Melanoma, Findings and Prognostic Value of FDG PET/CT: A Case Series of 23 patients and review of the literature.Asia Oceania journal of nuclear medicine & biology · 2022Article
- Proton beam therapy followed by pembrolizumab for giant ocular surface conjunctival malignant melanoma: A case report.Molecular and clinical oncology · 2022Article
- PET/CT and PET/MRI in ophthalmic oncology (Review).International journal of oncology · 2020Review
- Application of Multimodal and Molecular Imaging Techniques in the Detection of Choroidal Melanomas.Frontiers in oncology · 2020Review
- Observational
- Imaging Techniques in the Diagnosis and Management of Ocular Tumors: Prospects and Challenges.The AAPS journal · 2018Review
- Whole Body Positron Emission Tomography/Computed Tomography (PET/CT) in the Evaluation of Ophthalmic Tumors.Current medical science · 2018Article
- Dual-energy CT of liver metastases in patients with uveal melanoma.European journal of radiology open · 2016Article
- Poor Uptake of Fluorodeoxyglucose in Positron Emission Tomography-Computed Tomography Scan for Intraocular Choroidal Melanoma in Asian Indian Eyes.World journal of nuclear medicineArticle
- Lacrimal Sac Malignant Melanoma in 15 Japanese Patients: Case Report and Literature Review.Journal of investigative medicine high impact case reportsReview
- Prostate Cancer Detected by Choroidal Tumor and Complete Response to Hormonal Therapy: Case Report and Literature Review of 24 Patients With Choroidal Metastasis From Prostate Cancer.Journal of investigative medicine high impact case reportsReview
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe purpose of this study was to redefine the role of whole-body 2-[(18)F]fluoro-2-deoxy-D-glucose (FDG) positron emission tomography fused with computed tomography (PET/CT) in the clinical diagnosis of choroidal malignant melanoma.
methodsThe study design was a retrospective case series involving 7 consecutive patients with choroidal malignant melanoma who underwent enucleation to reach the final pathological diagnosis. FDG-PET/CT was performed together with magnetic resonance imaging and ophthalmological examinations before the surgery. The area, thickness, longest diameter, and circumference of the tumor mass were measured on pathological sections, and were correlated with maximum standardized uptake values (SUVmax) of the tumors on FDG-PET/CT.
resultsAbnormally high uptake of FDG was noted in the affected eyes of 5 patients, but not in the eyes of 2 patients. The 5 patients with high uptake showed nodular tumors extruding into the vitreous cavity while the 2 patients with absence of uptake showed diffusely infiltrating tumors in the wide area of the choroid with or without a small mushroom-like protrusion. One patient with diffuse infiltration showed concurrent liver metastases with high uptake on PET/CT while another patient with a nodular tumor developed liver metastases a year later. The tumors with higher SUVmax had a tendency to have a wider area and greater thickness on pathological sections (ρ = 0.775, P = 0.0557, Spearman rank correlation test).
conclusionsFDG-PET/CT showed correlation of the uptake with tumor sizes but was limited in detecting diffusely infiltrating tumors in the choroid without nodular formation.
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