ArticleEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2013
Risk factors for survival of 106 surgically treated patients with symptomatic spinal epidural metastases.
Article in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 4 of them syntheses that pooled it.
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16 citing papers in PubMed, 4 syntheses or guidelines pooled it, 46 citations in OpenAlex.
- Prognostic factors and outcomes of surgical intervention for patients with spinal metastases secondary to lung cancer: an update systematic review and meta analysis.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2023Pooled it
- Surgical complications and re-operation rates in spinal metastases surgery: a systematic review.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2021Pooled it
- Prevalence and risk factors of postoperative delirium after spinal surgery: a meta-analysis.Journal of orthopaedic surgery and research · 2020Pooled it
- Pooled it
- Post-operative complications affect survival in surgically treated metastatic spinal cord compression.International orthopaedics · 2024Article
- Development of a clinical prediction score for perioperative complications following metastatic spinal surgery (PERCOM) score.Heliyon · 2024Article
- Predicting Survival in Patients Presenting With Spinal Epidural Metastases: The Limburg Spinal Metastasis Score.International journal of spine surgery · 2023Article
- Impact of Obesity on Perioperative Complications on Treatment of Spinal Metastases: A Multicenter Surveillance Study from the German Spine Registry (DWG-Register).Asian journal of neurosurgery · 2022Article
- Impact of Obesity on Surgical Outcomes Following Laminectomy for Spinal Metastases.Global spine journal · 2019Article
- Hypoalbuminemia as an Independent Risk Factor for Perioperative Complications Following Surgical Decompression of Spinal Metastases.Global spine journal · 2019Article
- Age Stratification of 30-Day Postoperative Outcomes Following Excisional Laminectomy for Extradural Cervical and Thoracic Tumors.Global spine journal · 2018Article
- Treatment and outcomes of 28 patients with spinal metastasis from gynecological cancer.Journal of neuro-oncology · 2018Article
- Functional and survival outcomes in patients undergoing surgical treatment for metastatic disease of the spine.Journal of spine surgery (Hong Kong) · 2018Article
- Morphometrics predicts overall survival in patients with multiple myeloma spine metastasis: A retrospective cohort study.Surgical neurology international · 2018Article
- Molecular phenotype is associated with survival in breast cancer patients with spinal bone metastases.Clinical & experimental metastasis · 2015Article
- Prognostic factors associated with survival in patients with symptomatic spinal bone metastases: a retrospective cohort study of 1,043 patients.Neuro-oncology · 2014Article
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeEvaluation of risk factors for survival in patients surgically treated for symptomatic spinal epidural metastases (SEM).
methodsOne hundred and six patients who were surgically treated for symptomatic SEM in a 10-year period in two cooperatively working hospitals were retrospectively studied for nine risk factors: age, gender, site of the primary tumor, location of the symptomatic spinal metastasis, functional and neurologic status, the presence of visceral metastases and the presence of other spinal and extraspinal bone metastases. Analysis was performed using the Kaplan-Meier method, univariate log-rank tests and Cox-regression models.
resultsOverall median survival was 10.7 months (0.2-107.5 months). Overall 30-day complication rate was 33 %. Multivariate Cox-regression analysis showed that fast growing primary tumors (HR 3.1, 95 % CI 1.6-6.2, p = 0.001), the presence of visceral metastases (HR 1.7, 95 % CI 1.0-2.9, p = 0.033) and a low performance status (HR 2.7, 95 % CI 1.1-6.6, p = 0.025) negatively influenced the survival.
conclusionPrimary tumor type, presence of visceral metastases and performance status are significant predictors for survival after surgery for symptomatic SEM and should be evaluated before deciding on the extent of treatment. More accurate prediction models are needed to select the best treatment option for the individual patient.
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