Evidence map›Paper›PMID 23455923›Full record

ArticleNature methods2013

Ultrahigh accuracy imaging modality for super-localization microscopy.

Jerry Chao, Sripad Ram, E Sally Ward, Raimund J Ober

Abstract read
In one paragraph

Article in Nature methods, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Fisher information theory for parameter estimation in single molecule microscopy: tutorial.Journal of the Optical Society of America. A, Optics, image science, and vision · 2016
    Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Super-resolution fluorescence imaging with single molecules.Current opinion in structural biology · 2013
    Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jerry ChaoDepartment of Electrical Engineering, University of Texas at Dallas, Richardson, Texas, USA.
Sripad Ram
E Sally Ward
Raimund J Ober

Funding

High accuracy quantum dot tracking in live cellsR01GM085575 · NIGMS · UNIVERSITY OF TEXAS DALLAS · PI OBER, RAIMUND J · 2008 to 2016
$2.5M
NIGMS NIH HHS R01 GM085575
6 · The paper itself

Abstract

Super-localization microscopy encompasses techniques that depend on the accurate localization of individual molecules from generally low-light images. The obtainable localization accuracies, however, are ultimately limited by the image detector's pixelation and noise. We present the ultrahigh accuracy imaging modality (UAIM), which allows users to obtain accuracies approaching the accuracy that is achievable only in the absence of detector pixelation and noise, and which we found can experimentally provide a >200% accuracy improvement over conventional low-light imaging.

Indexed as

Equipment DesignFluorescenceLikelihood FunctionsMicroscopyPhotonsProtein TransportSignal Processing, Computer-AssistedStochastic Processes

Identifiers

PMID23455923
PMCPMC3833351

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.