Evidence map›Paper›PMID 23455909›Full record

ArticleJournal of the Optical Society of America. A, Optics, image science, and vision2012

Multimodal adaptive optics retinal imager: design and performance.

Daniel X Hammer, R Daniel Ferguson, Mircea Mujat, Ankit Patel, Emily Plumb, Nicusor Iftimia, Toco Y P Chui, James D Akula, Anne B Fulton

Open access · greenAbstract read
In one paragraph

Article in Journal of the Optical Society of America. A, Optics, image science, and vision, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
2.9field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 58 citations in OpenAlex.

  1. Trial
  2. Review
  3. Article
  4. The Surviving, Not Thriving, Photoreceptors in Patients withDiagnostics (Basel, Switzerland) · 2024
    Article
  5. Non-Rigid Registration for High-Resolution Retinal Imaging.Diagnostics (Basel, Switzerland) · 2023
    Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. The Fovea in Retinopathy of Prematurity.Investigative ophthalmology & visual science · 2020
    Article
  13. Article
  14. Article
  15. Biomedical optics express · 2018
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Daniel X HammerPhysical Sciences Inc., 20 New England Business Center, Andover, Massachusetts 01810, USA. dxhammer@gmail.com
R Daniel Ferguson
Mircea Mujat
Ankit Patel
Emily Plumb
Nicusor Iftimia
Toco Y P Chui
James D Akula
Anne B Fulton
Physical Sciences (United States) · USHarvard University · US

Funding

Photoreceptor Function in ROPR01EY010597 · NEI · CHILDREN'S HOSPITAL BOSTON · PI FULTON, ANNE B · 1994 to 2023
$10.7M
High Performance Multimodal Adaptive Optics Retinal ImagingR44EY018986 · NEI · PHYSICAL SCIENCES, INC · PI FERGUSON, R DANIEL · 2010 to 2011
$1.4M
Downregulation of Rod Metabolism in Retinopathy of PrematurityRC1EY020308 · NEI · BOSTON CHILDREN'S HOSPITAL · PI AKULA, JAMES DANIEL · 2009 to 2010
$790k
Multimode Adaptive Optics Retinal Imager for Diagnosis of Age-Related Macular DegR43EY018986 · NEI · PHYSICAL SCIENCES, INC · PI HAMMER, DANIEL X · 2008 to 2009
$378k
Adaptive Optics Imager for Study of Pediatric Retinal DisordersS10RR025605 · NCRR · BOSTON CHILDREN'S HOSPITAL · PI FULTON, ANNE B · 2009 to 2009
$365k
NCRR NIH HHS S10 RR025605NCRR NIH HHS S10RR025605NEI NIH HHS EY010597NEI NIH HHS EY018986NEI NIH HHS EY020308NEI NIH HHS R01 EY010597NEI NIH HHS R43 EY018986NEI NIH HHS R44 EY018986NEI NIH HHS RC1 EY020308
6 · The paper itself

Abstract

Optical coherence tomography (OCT) and scanning laser ophthalmoscopy (SLO) are complementary imaging modalities, the combination of which can provide clinicians with a wealth of information to detect retinal diseases, monitor disease progression, or assess new therapies. Adaptive optics (AO) is a tool that enables correction of wavefront distortions from ocular aberrations. We have developed a multimodal adaptive optics system (MAOS) for high-resolution multifunctional use in a variety of research and clinical applications. The system integrates both OCT and SLO imaging channels into an AO beam path. The optics and hardware were designed with specific features for simultaneous SLO/OCT output, for high-fidelity AO correction, for use in humans, primates, and small animals, and for efficient location and orientation of retinal regions of interest. The MAOS system was tested on human subjects and rodents. The design, performance characterization, and initial representative results from the human and animal studies are presented and discussed.

Indexed as

OphthalmoscopesAdultAnimalsEquipment DesignHumansLasersRatsRats, Sprague-DawleyRetinaTomography, Optical Coherence

Identifiers

PMID23455909
PMCPMC6360942
OpenAlexW2021513243

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.