Trial reportExperimental brain research2013
Effects of prefrontal repetitive transcranial magnetic stimulation on the autonomic regulation of cardiovascular function.
Trial report in Experimental brain research, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04210557 (Models of Auditory Hallucination), which is not on this map. Cited by 13 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Models of Auditory Hallucination
Who cites it
13 citing papers in PubMed.
- Deep transcranial magnetic stimulation in combination with skin thermography in obesity: a window on sympathetic nervous system.Acta diabetologica · 2022Trial
- Induced effects of transcranial magnetic stimulation on the autonomic nervous system and the cardiac rhythm.TheScientificWorldJournal · 2014Trial
- Atrial fibrillation detected after ischemic stroke (AFDAS) diagnosed by short-term monitoring: the importance of frontal hypoperfusion.Journal of thrombosis and thrombolysis · 2026Article
- Repetitive transcranial magnetic stimulation ameliorates myocardial injury in vascular dementia via renin-angiotensin system modulation.Neuroreport · 2025Article
- Autonomic Imbalance in Cardiomyopathy and Heart Failure: From Neurobiology to Precision Neuromodulation.Current cardiology reports · 2025Review
- Neuromodulation of the Cardiac Autonomic Nervous System for Arrhythmia Treatment.Biomedicines · 2025Review
- Severe bradycardia triggered by repetitive transcranial magnetic stimulation in a patient with major depressive disorder and premature ventricular contractions: a case report.BMC psychiatry · 2025Article
- Case Report: Peripheral combined central dual-target magnetic stimulation for non- motor symptoms of Parkinson's disease.Frontiers in psychiatry · 2025Article
- Inhibitory Control and Brain-Heart Interaction: An HRV-EEG Study.Brain sciences · 2022Article
- Autonomic Neural Circuit and Intervention for Comorbidity Anxiety and Cardiovascular Disease.Frontiers in physiology · 2022Review
- Safety and tolerability of repeated sessions of deep transcranial magnetic stimulation in obesity.Endocrine · 2021Article
- Article
- Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Several protocols based on repetitive transcranial magnetic stimulation (rTMS) have been proposed for treatment of a variety of neurological disorders. Despite the widespread use, little is known about the effects of rTMS on the autonomic nervous control of the cardiovascular system. Twelve volunteers underwent rTMS sessions consisted in 8-min baseline recording, 8-min 0.7-Hz rTMS stimulation at 100 % of the motor cortex excitability threshold on the prefrontal cortex of one randomly assigned hemisphere. After 8-min recovery, the same procedure was performed on the contra-lateral hemisphere. Non-invasive (Portapres device) beat-by-beat blood pressure and heart period time series were recorded and analyzed by spectral and cross-spectral analysis in the low-frequency (LF ≈ 0.1 Hz) and in the high-frequency (HF = respiratory frequency) range. Repetitive TMS, particularly after stimulation of the right hemisphere, induced a slight increase in the parasympathetic drive and no effects on the sympathetic activity. There was a significant bradycardia after stimulation on the right hemisphere, not significant bradycardia after left stimulation. LF/HF ratio was 3.8 ± 2.1 during baseline and changed to 1.9 ± 0.6 during rTMS on the left and to 1.6 ± 0.6 during rTMS on the right. No significant changes were observed in blood pressure. Low-frequency rTMS of the prefrontal cortex induces a slight parasympathetic activation and no changes in the sympathetic function.
Indexed as
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.