ReviewNutrients2013
Gut microbiota as potential therapeutic target for the treatment of cow's milk allergy.
Review in Nutrients, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 39 citations in OpenAlex.
- Shared epigenetic mechanisms in atopic dermatitis and food allergy: a review of immune dysregulation at the skin-gut axis.Skin health and disease · 2026Review
- Duration of food protein-induced allergic proctocolitis (FPIAP) and the role of intestinal microbiota.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2024Observational
- Research progress on the mechanism of probiotics regulating cow milk allergy in early childhood and its application in hypoallergenic infant formula.Frontiers in nutrition · 2024Review
- Food allergy: cause or consequence of pediatric eosinophilic esophagitis? Potential implications of ultraprocessed foods in prevention and management.Frontiers in allergy · 2023Review
- Fructo-Oligosaccharide Alleviates Soybean-Induced Anaphylaxis in Piglets by Modulating Gut Microbes.Frontiers in microbiology · 2018Article
- Prevention and Management of Cow's Milk Allergy in Non-Exclusively Breastfed Infants.Nutrients · 2017Review
- Early-life gut microbiome composition and milk allergy resolution.The Journal of allergy and clinical immunology · 2016Observational
- The controversial role of food allergy in infantile colic: evidence and clinical management.Nutrients · 2015Review
- Cow's milk allergy: from allergens to new forms of diagnosis, therapy and prevention.Methods (San Diego, Calif.) · 2014Article
- Synbiotics in Children with Cow's Milk Allergy: A Randomized Controlled Trial.Iranian journal of pediatrics · 2014Article
- The role of infant nutrition in the prevention of future disease.Frontiers in pediatrics · 2014Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cow's milk allergy (CMA) continues to be a growing health concern for infants living in Western countries. The long-term prognosis for the majority of affected infants is good, with about 80% naturally acquiring tolerance by the age of four years. However, recent studies suggest that the natural history of CMA is changing, with an increasing persistence until later ages. The pathogenesis of CMA, as well as oral tolerance, is complex and not completely known, although numerous studies implicate gut-associated immunity and enteric microflora, and it has been suggested that an altered composition of intestinal microflora results in an unbalanced local and systemic immune response to food allergens. In addition, there are qualitative and quantitative differences in the composition of gut microbiota between patients affected by CMA and healthy infants. These findings prompt the concept that specific beneficial bacteria from the human intestinal microflora, designated probiotics, could restore intestinal homeostasis and prevent or alleviate allergy, at least in part by interacting with the intestinal immune cells. The aim of this paper is to review what is currently known about the use of probiotics as dietary supplements in CMA.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.