ArticleEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2013
Nasal douches for diseases of the nose and the paranasal sinuses--a comparative in vitro investigation.
Article in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02559284 (A Comparative, Multicenter and Randomized Study Evaluating the Safety and Efficacy of RESPIMER® Netiflow® Versus Saline Solutions During Nasal Irrigation Following Bilateral Ethmoidectomy in the Treatment of Nasal Polyposis.), which is not on this map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Comparative, Multicenter and Randomized Study Evaluating the Safety and Efficacy of RESPIMER® Netiflow® Versus Saline Solutions During Nasal Irrigation Following Bilateral Ethmoidectomy in the Treatment of Nasal Polyposis.
Who cites it
12 citing papers in PubMed, 34 citations in OpenAlex.
- Prospective, randomized, controlled, open-label study to compare efficacy of a mineral-rich solution vs normal saline after complete ethmoidectomy.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2019Trial
- Flow rate selection depends on the size of allergen particles to achieve optimal nasal irrigation.Scientific reports · 2025Article
- The Diagnosis and Treatment of Chronic Rhinosinusitis.Deutsches Arzteblatt international · 2024Review
- A novel irrigation device with superior nasal irrigation efficiency to the classic rinse bottle.Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale · 2022Article
- Current Perspective on Nasal Delivery Systems for Chronic Rhinosinusitis.Pharmaceutics · 2021Review
- A multicenter survey on the effectiveness of nasal irrigation devices in rhinosinusitis patients.Laryngoscope investigative otolaryngology · 2020Article
- Nasal lavage containing Angiotensin-Converting Enzyme-2 agonist can prevent and reduce viral load in COVID-19.Medical hypotheses · 2020Article
- Article
- Review
- Nasal Irrigation: An Imprecisely Defined Medical Procedure.International journal of environmental research and public health · 2017Review
- Comprehensive review on endonasal endoscopic sinus surgery.GMS current topics in otorhinolaryngology, head and neck surgery · 2015Review
- Practices and Techniques of Jal Neti Across Indian Institutions: A Cross-sectional Study.International journal of yogaArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Nasal douches are applied in great number of diseases of the nose and the paranasal sinuses. For this purpose, many different kinds of nasal douching systems have been introduced into the market. The aim of this study was to examine the irrigation characteristics of the current nasal douching systems. In this context, 26 nasal douching systems were compared regarding irrigation volume, irrigation duration, flow rate and pressure and course of the irrigation stream. The following procedure was applied: First, the spontaneous flow through the nasal douche was measured, then the flow under compression. Finally, these procedures were repeated using a nose model. Furthermore, we asked the manufacturers for information concerning possible cleaning and disinfection techniques. Douching period and flow rate highly depend on physical parameters: distance between liquid column and outlet (hydrostatic pressure) and form and size of the outlet (energy loss because of friction/turbulence). A weak irrigation stream was found in spontaneous release of the douching system when both douching pressure and flow rate offered low values. The douching of the nose model showed that the incompressible nasal douches only reached the lower nasal passage. Only the compressible nasal douching systems led to a diffuse moisturization as well as to a perfusion of the entire nasal cavity. Systematic evaluation of the different recommended cleaning and disinfection methods of the nasal douching systems is still missing. Nasal douches are often recommended in many diseases of the nose and the paranasal sinuses. In this comparative in vitro study, physical parameters and material properties of the nasal douching systems were examined for the first time. For irrigation of the whole nasal cavity and paranasal sinuses, compressible douching systems are recommended which have a minimum output pressure of 120 mbar, a good connection of the outlet to the nostril with a possible insertion into the nasal vestibule and an irrigation stream which is directed upwards (45°). The material should be transparent, easy to clean and disinfect and should not contain harmful elements.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.