Evidence map›Paper›PMID 23455494›Full record

ArticleCurrent microbiology2013

Chromobacterium violaceum: important insights for virulence and biotechnological potential by exoproteomic studies.

Alessandra Ciprandi, Wanderson Marques da Silva, Agenor Valadares Santos, Adriano Monteiro de Castro Pimenta, Marta Sofia Peixe Carepo, Maria Paula Cruz Schneider, Vasco Azevedo, Artur Silva

Open access · hybridAbstract read
In one paragraph

Article in Current microbiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Regulation of virulence inFrontiers in microbiology · 2024
    Review
  6. The impact ofJournal of genomics · 2024
    Article
  7. Review
  8. Effect of Essential Oils ofMicroorganisms · 2023
    Article
  9. Metabolomic Analysis of the Effect ofAntibiotics (Basel, Switzerland) · 2023
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Alessandra CiprandiNúcleo de Medicina Tropical, Universidade Federal do Pará, Av. Gen. Deodoro 92, Belém 66055-240, Brazil. alecip@gmail.com
Wanderson Marques da Silva
Agenor Valadares Santos
Adriano Monteiro de Castro Pimenta
Marta Sofia Peixe Carepo
Maria Paula Cruz Schneider
Vasco Azevedo
Artur Silva
Universidade Federal do Pará · BRUniversidade Federal de Minas Gerais · BRRede de Química e Tecnologia · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chromobacterium violaceum is a beta-proteobacterium with high biotechnological potential, found in tropical environments. This bacterium causes opportunistic infections in both humans and animals, that can spread throughout several tissues, quickly leading to the death of the host. Genomic studies identified potential mechanisms of pathogenicity but no further studies were done to confirm the expression of these systems. In this study 36 unique protein entries were identified in databank from a two-dimensional profile of C. violaceum secreted proteins. Chromobacterium violaceum exoproteomic preliminary studies confirmed the production of proteins identified as virulence factors (such as a collagenase, flagellum proteins, metallopeptidases, and toxins), allowing us to better understand its pathogenicity mechanisms. Biotechnologically interesting proteins (such as chitinase and chitosanase) were also identified among the secreted proteins, as well as proteins involved in the transport and capture of amino acids, carbohydrates, and oxidative stress protection. Overall, the secreted proteins identified provide us important insights on pathogenicity mechanisms, biotechnological potential, and environment adaptation of C. violaceum.

Indexed as

AnimalsBacterial ProteinsBiotechnologyChromobacteriumElectrophoresis, Gel, Two-DimensionalEnvironmental MicrobiologyGram-Negative Bacterial InfectionsHumansIndustrial MicrobiologyMass SpectrometryProteomeVirulence FactorsBacterial ProteinsProteomeVirulence Factors

Identifiers

PMID23455494
PMCPMC3661913
OpenAlexW2126878664

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.