Evidence map›Paper›PMID 23455383›Full record

ArticleEuropean journal of nutrition2013

Nutrient reference values for bioactives: new approaches needed? A conference report.

Hans Konrad Biesalski, John W Erdman, John Hathcock, Kathleen Ellwood, Stephen Beatty, Elizabeth Johnson, Roberto Marchioli, Lotte Lauritzen, Harry B Rice, Andrew Shao and 1 more

Abstract readConference Proceedings
In one paragraph

Article in European journal of nutrition, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  18. Bioactive foods and ingredients for health.Advances in nutrition (Bethesda, Md.) · 2014
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

Hans Konrad BiesalskiUniversity of Hohenheim, Stuttgart, Germany.
John W Erdman
John Hathcock
Kathleen Ellwood
Stephen Beatty
Elizabeth Johnson
Roberto Marchioli
Lotte Lauritzen
Harry B Rice
Andrew Shao
James C Griffiths

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nutrients can be classified as either "essential" or "non-essential," the latter are also termed bioactive substances. Whereas the absence of essential nutrients from the diet results in overt deficiency often times with moderate to severe physiological decrements, the absence of bioactive substances from the diet results in suboptimal health. Nutrient reference values are set by Codex Alimentarius and regulatory bodies in many countries, mostly for essential nutrients with recommended daily intakes. The IOM in the United States has defined a set of four DRIs that, when data are appropriate, include an EAR, a RDA that is derived from the EAR, an AI for nutrients without appropriate data to identify an EAR, and an UL. From the RDA, the United States derives a labeling value called the DV, which applies to older children and most adults. In Codex, the equivalents of the DVs are the NRVs to be used in calculating percentage values on food labels. Nothing in the IOM documents specifies that labeling values can be set only for what have been defined to date as essential nutrients. Indeed, the US Food and Drug Administration sets a labeling value for dietary fiber based on the IOM AI for this ingredient. This conference explores the definitions, concepts, and data on two of the best examples of bioactive substances that, perhaps, should have NRVs: lutein and zeaxanthin, and n-3 long-chain polyunsaturated fatty acids.

Indexed as

DietFatty Acids, Omega-3LuteinNutrition PolicyXanthophyllsBrainCarotenoidsChildFoodFood LabelingHealth PromotionHumansMacular DegenerationNutritional RequirementsReference ValuesUnited StatesCarotenoidsFatty Acids, Omega-3LuteinXanthophyllsZeaxanthins

Identifiers

PMID23455383
PMCPMC3597284

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.