ArticleApplied and environmental microbiology2013
Characteristics of extended-spectrum β-lactamase- and carbapenemase-producing Enterobacteriaceae Isolates from rivers and lakes in Switzerland.
Article in Applied and environmental microbiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 111 papers, 1 of them a synthesis that pooled it.
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Who cites it
111 citing papers in PubMed, 1 synthesis or guideline pooled it, 272 citations in OpenAlex.
- The spread of carbapenemase-producing bacteria in Africa: a systematic review.The Journal of antimicrobial chemotherapy · 2015Pooled it
- Role of extended-spectrum β-lactamase (ESBL) genes in the dissemination of β-lactam resistance within aquatic environments: mechanisms, persistence, and one health implications.World journal of microbiology & biotechnology · 2026Review
- Genomic characterization of carbapenem-resistant Gram-negative bacilli isolated from hospital wastewater in Niamey, Niger.IJID regions · 2026Article
- One Health transmission of plasmid-mediated antimicrobial resistance: genomic insights at the interface of food, animals, humans and the environment.JAC-antimicrobial resistance · 2026Review
- Diversity and Antimicrobial Resistance Profiles of ESBL-ProducingPathogens (Basel, Switzerland) · 2026Article
- The Emergence ofAntibiotics (Basel, Switzerland) · 2025Article
- Multidrug-resistant E. Coli in wastewater sources: a comparative study and identification of resistance hotspots.BMC microbiology · 2025Article
- Environmental Dispersion of MultiresistantAntibiotics (Basel, Switzerland) · 2025Article
- Carbapenem-resistant bacteria in the environment.Arhiv za higijenu rada i toksikologiju · 2025Review
- Molecular Characterization of Extended-Spectrum ß-Lactamases-ProducingAntibiotics (Basel, Switzerland) · 2025Article
- Multidrug-resistant ESBLHeliyon · 2025Article
- Urban wastewater overflows as hotspots for dissemination of bacteria producing extended-spectrum β-lactamases and carbapenemases in the Suquía River, Argentina.Frontiers in microbiology · 2025Article
- Occurrence and molecular detection of antibiotic-resistant genes inSustainable microbiology · 2025Article
- Enterobacterales Producing ESBLs and AmpC in Fresh Vegetables from Tebessa City, Algeria.Microbial drug resistance (Larchmont, N.Y.) · 2024Article
- Antimicrobial Susceptibility and Genetic Epidemiology of Extended-Spectrum β-Lactamase-Positive Enterobacterales Clinical Isolates in Central Poland.International journal of molecular sciences · 2024Article
- High Prevalence of ESBL Genes in CommensalGenes · 2024Article
- Carbapenem-Resistant NDM and OXA-48-Antibiotics (Basel, Switzerland) · 2024Article
- Freshwater and Marine Environments in California Are a Reservoir of Carbapenem-Resistant Bacteria.Microorganisms · 2024Article
- A rare case of multi-drug resistantClinical case reports · 2024Article
- Carbapenemase-producing bacteria recovered from Nairobi River, Kenya surface water and from nearby anthropogenic and zoonotic sources.PloS one · 2024Article
51 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
One of the currently most relevant resistance mechanisms in Enterobacteriaceae is the production of enzymes that lead to modern expanded-spectrum cephalosporin and even carbapenem resistance, mainly extended-spectrum β-lactamases (ESBLs) and carbapenemases. A worrisome aspect is the spread of ESBL and carbapenemase producers into the environment. The aim of the present study was to assess the occurrence of ESBL- and carbapenemase-producing Enterobacteriaceae and to further characterize ESBL- and carbapenemase-producing Enterobacteriaceae in rivers and lakes in Switzerland. ESBL-producing Enterobacteriaceae were detected in 21 (36.2%) of the 58 bodies of water sampled. One river sample tested positive for a carbapenemase-producing Klebsiella pneumoniae subsp. pneumoniae strain. Seventy-four individual strains expressing an ESBL phenotype were isolated. Species identification revealed 60 Escherichia coli strains, seven Klebsiella pneumoniae subsp. pneumoniae strains, five Raoultella planticola strains, one Enterobacter cloacae strain, and one Enterobacter amnigenus strain. Three strains were identified as SHV-12 ESBL producers, and 71 strains carried genes encoding CTX-M ESBLs. Of the 71 strains with CTX-M ESBL genes, 8 isolates expressed CTX-M-1, three produced CTX-M-3, 46 produced CTX-M-15, three produced CTX-M-55, one produced CTX-M-79, six produced CTX-M-14, and four produced CTX-M-27. Three of the four CTX-M-27 producers belonged to the multiresistant pandemic sequence type E. coli B2:ST131 that is strongly associated with potentially severe infections in humans and animals.
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