Evidence map›Paper›PMID 23455022›Full record

ArticlePlant signaling & behavior2013

Function of Arabidopsis CPL1 in cadmium responses.

Emre Aksoy, Hisashi Koiwa

Abstract read
In one paragraph

Article in Plant signaling & behavior, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Emre AksoyMolecular and Environmental Plant Sciences; Vegetable and Fruit Development Center; Department of Horticultural Sciences; Texas A&M University; College Station, TX USA.
Hisashi Koiwa

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Transcriptional and post-transcriptional responses to external iron (Fe) availability are essential for the cellular Fe homeostasis. Fe deficiency strongly induces Fe utilization-related gene expression; however, little is known about the early Fe signaling that regulates expression of a central transcription factor FIT. In Arabidopsis, mutations in RNA polymerase II CTD-phosphatase-like 1 (CPL1) enhance the expression of Fe utilization-related genes including FIT under Fe deficiency. Fe content is significantly increased in the roots and decreased in the shoots of cpl1-2 plants, and root growth of the cpl1-2 mutant shows higher tolerance to Fe deficiency and to toxicity of cadmium (Cd). The cpl1-2 plants accumulate more Cd in the shoots, suggesting that Cd toxicity in the cpl1-2 roots is circumvented by the transport of excess Cd to the shoots. Here we show data suggesting that the root-to-shoot translocation of Cd in cpl1-2 is mediated by yet uncharacterized Cd transport mechanisms.

Indexed as

ArabidopsisArabidopsis ProteinsCadmiumGene Expression Regulation, PlantMembrane Transport ProteinsPhosphoprotein PhosphatasesReverse Transcriptase Polymerase Chain ReactionRNA-Binding ProteinsTranscription FactorsArabidopsis ProteinsCadmiumCPL1 protein, ArabidopsisMembrane Transport ProteinsPhosphoprotein PhosphatasesRNA-Binding ProteinsTranscription FactorscadmiumCPL1CTDFITFRO2ironIRT1signalingstresstranscription

Identifiers

PMID23455022
PMCPMC3897498

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.